Biomedical subjects

B Fjällbrant

Publications and source records attributed to B Fjällbrant.

At least 19 recordsLinked to original sources

PubMed1981

Computer-aided counting with the Coulter Counter of low numbers of spermatozoa in human semen.

The concentration of spermatozoa in human semen has been assessed by counting in the microscope with a hemocytometer and by counting with the Coulter Counter ZF. The Coulter Counter was supplied with a 100-channel pulseheight analyzer, Channelyzer C-1000, and a tape-punch for further handling of data in a desk-computer. It was found that the number of spermatozoa (less than 10(6) per ml) was over-estimated with the Coulter Counter. By subtraction of the non-spermatozoan background with the aid of mathematical curve-fitting procedures, these values could be corrected. To allow such an adequate analysis without the use of pulse-height analyzer and computer, the background corrections were simulated for the relative number of counts obtained at specified setting of the threshold levels (T) and other variables on the Coulter Counter ZF.

Computers↗

PubMed1977

Decrease of sperm antibody titer in males, and conception after treatment of chronic prostatitis.

Although autoimmunization to spermatozoa is a cause of male infertility, the cause of antibody formation is unknown in most cases. It has been shown that the titer is usually unchanged for as much as 16 years in the same individual. Trials to reduce the titer with varying methods have not been successful. A new possibility of treatment was indicated by the finding of a higher incidence of prostatitis in men with sperm antibodies than in a control group. Following treatment of prostatitis we observed a reduction of the antibody titer in eight cases. In five cases the cervical mucus penetrating capacity of the spermatozoa improved, and conception occurred.

Autoantibodies↗

PubMed1975

Autoimmune human sperm antibodies and age in males.

The incidence of autoimmunization to spermatozoa, investigated by means of the Kibrick technique, increased with age in 913 males unselected with regard to fertility. By contrast, the incidence of sperm agglutinin-postive sera decreased with age in 1600 male partners in sterile couples. The increasing incidence of autoimmunization to spermatozoa offers one explanation of the lowering of fertility with increasing age, but sperm antibodies seem to be more important as a cause of sterility at younger ages. The presence of spermatozoa may not be necessary for immunization since sperm agglutinins were found in a 9-year-old boy.

Adolescent↗

PubMed1975

Tubal surgery. Report of 101 cases with special reference to the experience of the surgeon.

A report is given of the results of tubal surgery in 101 cases selected from 851 sterility patients. The follow-up time was 3-10 years. Ordinary surgical technique was applied with the use of prednisolone and antibiotics but largely without the use of polyethylene tubing or other splints. Fourteen surgeons were involved. Since the most experienced surgeon operated on about 30% of the cases, an assessment of the effect of the surgeon's skill was possible. The patients are divided into groups with regard to type of operation, and the result is judged with regard to conception, live birth, ectopic pregnancy and abortion as well as with regard to patency. After salpingolysis the conception rate was 52%, and after salpingostomy 32%. There was, however, a gap between the conception rate and the live birth rate, especially for the salpingostomy cases. The live birth rate was more than twice as high after salpingolysis than after salpingostomy. The small lasting effect of cut adhesions is also demonstrated by the observation that combined unilateral or bilateral lysis did not interfere with the result after salpingostomy. Contrary to this, the patients conceived faster after salpingostomy than after salpingolysis. There was no difference between the results in the patients operated on by the most experienced surgeon and in those treated by the thirteen less skilled gynecologists.

Clinical Competence↗

PubMed1974