Biomedical subjects
Publications and source records attributed to B Foucou.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Spigel's lobe, or segment I of the liver, currently represents the "smallest amount of hepatic parenchyma capable of regeneration". It is an autonomous lobe by virtue of its site and vasculo-biliary distribution, a true "accessory" liver connected to the "main" liver. Lesions of Spigel's lobe are rare, which is explained by the anatomy of the portal bifurcation. Hence the value of making every effort to preserve this segment during hepatectomy because of the possibilities of additional hepatic vein drainage. Segment I surgery is difficult and falls within the context of extended hepatectomies. Can Spigel's lobe be considered to be a "safety liver"? The possibility of subtotal hepatectomy, retaining only segment I, is being studied in the animal. It may be possible in man in the case of extensive hepatic lesions where only segment I is unaffected, as soon as effective artificial liver support is developed.
Explore the source record for details and available documents.
To look for the explanation about the post-cholecystectomy syndrome, the authors study 637 liver's biopsies during cholecystectomy for cholelithiasis. 373 liver's biopsies showed hepatic lesions (58.5 per cent). The post-cholecystectomy syndrome is observed in 36 per cent of patients who had hepatic lesions, and only 13 per cent of patients with normal liver biopsies.
Single photon emission computed tomography was used to evaluate the total functioning liver mass and the regeneration process after partial hepatectomy. Serial tomographic sections were performed after infusion of 99m Technetium. In studies on dogs and in human beings, computed gammatomography enabled to calculate the liver mass with less than 10 p. 100 error. Hepatic regeneration was studied in 10 patients following resection of 46 to 84 p. 100 of the initial liver mass. The remaining liver mass increased rapidly postoperatively and doubled within 13 to 18 days. The regeneration process followed an exponential curve. Assessment of liver regeneration by this non-invasive technique should be of great help following partial hepatectomy.
The technical problems raised by the delicate surgery of tumours of the liver developing around the vena cava, with and without invasion of segments I and IX was studied on the basis of 7 cases reports. The intra- or extra-hepatic pedicule route, the denudation of the entire retrohepatic vena cava, and the clamping needed for exsanguinous surgery are presented together with future perspectives including 3-D liver imaging, stimulation of liver regeneration potential and ex-vivo techniques are discussed with the aim of more and more carcinological liver surgery.