Biomedical subjects
Publications and source records attributed to B Frachet.
A method for conducting "brain stem early derived potentials" using an inexpensive microcomputer is described. This type of examination is, however, difficult to perform, and is not currently employed in clinical practice. The contribution offered by this data-processing system is emphasized.
The Brain stem evoked response audiometry have been studied in 34 cases of multiple sclerosis. The Brainstem in 8 cases were normal and abnormal on one or both sides in the remaining 26 cases (73.5 p. 100). A Brainstem is considered suspicious of multiple sclerosis when the first wave (N1) is normal as far as the time period is concerned, although there is a loss of synchronisation of the recording particularly as far as the higher part of the brain stem (N4 and N5). In 24 cases of multiple sclerosis of definite diagnosis (according to Mac Alpine criteria) 19 cases had abnormal recordings (79.2 p. 100). In 31 cases that had a neurological test showing a lesion of the brain stem, 23 cases of evoked potentials were abnormal (74.2 p. 100). In 3 cases that clinicaly had no lesion of the brain stem, the evoked potentials were abnormal in 2 of them, suggesting the eventuality of a lesion clinicaly non-reactive which can then be of help to confirm the diagnosis.
The finding of the frequent association in the infant of endothoracic tracheal compression and of GOR leads to discussion of their pathogenic link. In cases of endothoracic compression, manometric recording demonstrates the presence of an inversion of intragastric pressures with expiratory hyperpressure and a decrease in anti-reflux gradient. These data represent an argument in favour of medical anti-reflux treatment following discovery during endoscopic investigations for chronic or recurrent bronchopneumonia of the association of tracheal compression and gastrooesophageal reflux. Manometry should make it possible, where medical treatment proves unsatisfactory, to differentiate those cases where anti-reflux surgery is justified and those requiring a decompression procedure.
This study of the Brainstem evoked Response has been done to try to find the exact location of neurologic disorders. The authors wanted to see if there were differences between normal subjects and patients with multilocular sclerosis, when the auditory stimulus in increasing from 10 pps to 50 pps. From 15 normal subjects (30 ears) the results have been compared to those obtained from 6 patients. The findings were: -- there is no adaptation phenomenon in the Brainstem (the conduction time in the Brainstem is absolutely constant). -- there is an adaptation which occurs before the first peak, happening later at 50 pps than at 10 pps. -- in the multilocular sclerosis the findings were: augmentation of the peak to peak delay no synchronisation of the peaks so that is very difficult to recognize each peaks. And the peaks are easier to recognize at 50 pps than at 10 pps which fact unexpectable. This dyssynchronisation at the compression and rarefaction click is for the authors an important factor for the multilocular sclerosis diagnosis.
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This study involves the frequency, techniques and results of follow-up surgery for carcinoma of the tonsil treated by transcutaneous radiotherapy. Local or lymph node failures affect 65% of patients treated by radiation. Follow-up surgery was used in 86% of these failures. After reviewing the various techniques and their oncological results, the authors discuss the best timing for follow-up surgery. They compar their results of surgery in the case of sub-total treatment, surgery for recurrences and routine surgery two months after the end of transcutaneous irradiation. The results are in favour of routine surgery. If it is accepted, since this point is open to discussion, that radiotherapy remains the appropriate initial, and sometimes adequate, treatment for carcinoma of the tonsil, the frequency of local and lymph node recurrences should lead to the indication, in certain cases, for complementary surgical therapy. This routine additional surgical treatment should be discussed in the context of the initial protocol of the treatment of a carcinoma of the tonsil.
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Explore the source record for details and available documents.