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Biomedical subjects

B Fuchs

Publications and source records attributed to B Fuchs.

At least 37 records · Page 2Linked to original sources

[The prevalence of bronchial asthma in a selected sample of the adult Prague population].

The authors assessed the prevalence of bronchial asthma in 8458 18-year-old and older inhabitants of an economic area in Prague 8. The population of the area up to December 31, 1987 was 90,458 adults. The health communities were selected in a random way to comprise the central as well as peripheral parts of Prague 8. By means of questionnaires information was assembled from 70.9% of the respondents and after supplementation of data by various doctors the scope of information was 89.9% (7605/8458). For detailed examination 902 subjects were selected with "confirmed" and suspect symptoms of asthma. The anamnestic data were analyzed and pulmonary ventilation was examined (flow-volume), and depending on indication, also the provocation or bronchodilatation inhalation test, skin tests, and total IgE. The cumulative prevalence of bronchial asthma was 2.3% +/- 0.3% (174/7605). The highest prevalence values were in subjects under 20 years--3.5% and under 30 years--3.6%. The contemporary prevalence was 2.0% +/- 0.3% (152/7605). Nonatopic asthma was recorded in 54%, atopic asthma in 46% of the subjects.

Adolescent

Assessment of insulin needs in insulin-dependent diabetics and healthy volunteers under fasting conditions.

It is known from clinical observations, theoretical investigations as well as from data patients with intensified insulin therapy and wearers of insulin pumps that the body also requires insulin under fasting conditions. Therapeutic studies as well as the investigations carried out using the artificial pancreas indicate that just under half of the daily insulin requirement is not meal-related, and the other half is dependent on food. The question arose as to whether there are any differences in the basal insulin requirement depending on the time of day and whether differences can be detected between type I diabetics and healthy reference subjects. The results show that analogous changes occur in the early hours of the morning in type I diabetics and healthy normal subjects: these correspond to the clinical familiar dawn phenomenon. The different courses of blood glucose and insulin requirement as measured on the basis of the release of insulin by the Biostator as well as the insulin secretion profile in healthy normal volunteers under fasting conditions do not show any further differences which depend on the time of day.

Adult

[Vascular tumors of the lungs].

A series of nine vascular tumors of the lungs, five of them being benign hemangiomas, three hemangiosarcomas and one hemangiopericytoma is presented. In five patients the disease was detected on the basis of subjective complaints which indicated necessary hospitalization, in the other four patients the tumours were revealed by chance during preventive X-ray examination or X-ray examination for other causes. These patients were admitted to hospital for progression of lung changes. Five of the patients underwent surgery, lobectomy, was made in two cases, the other patients were treated by segmental, V-shape or atypical lung resection. Patients with benign hemangiomas manifested the best prognosis even in those where surgery was not possible. In cases of hemangiosarcoma or hemangiopericytoma the outlook is exceptionally serious even in primary forms. In the preoperation diagnostics of arteriovenous hemangiomas the tomographic examination and lung angiography represents an important help, in the other vascular tumours it is particularly CT and lung biopsy.

Adult

[Pathogenesis and clinical aspects of Reinke edema. Long-term studies].

Since 1973, 307 patients have been treated for Reinke's oedema in the ENT Department of the University of Marburg. A retrospective study from 1983 and observations up to 1989 investigated the aetiology and the prognosis of the disease. Two aetiological factors were found: smoking and voice abuse. Surgical treatment, stripping of the vocal cords as described by Kleinsasser was successful. There were no recurrences and no malignant degenerations. The prognosis was considered to be good. Two other long-term studies of Reinke's oedema are compared with our findings. Controversial opinions about the therapy are discussed.

Adult

[Benign tumors of the lungs and bronchi].

Results of a retrospective study from the years 1961 to 1986 have been presented based on hospitalization of 292 patients with benign tumours of the lungs and bronchi verified by histology. The prevailing tumours in the cohort were chondrohamartomas (62.0%) and carcinoids (21.9%). The tumours were localized more frequently inside the parenchyma (75.7%) than inside the bronchi (24.3%). The patients were men in 59.9% and women in 40.1%, the mean age during hospitalization being 48.8 years. In 60.6% of the patients the tumours were detected during an accidental radiographic examination, the tumour increased in size over several years of observation in 22.6% of the patients. A total of 280 patients (95.5%) were surgically treated, the tumour was removed in the bronchoscopic way in nine cases, two patients could not be operated on for advanced processes and one patient refused the operation. In 83.2% of the patients the surgical intervention was smaller than lobectomy, larger interventions prevailed in endobronchial localization making 54% on the whole, bronchial carcinoids being 71% of these.

Bronchial Neoplasms

[Lung cysts].

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Adult