Lactate accumulation in methanol poisoning.
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Biomedical subjects
Publications and source records attributed to B Futeral.
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A double-blind trial was designed to investigate the efficacy of low-dose heparin in preventing deep-vein thrombosis (DVT) after open prostatectomy... The diagnosis of DVT was established by the 125I-fibrinogen test. The incidence of DVT was 39.4% in the control group (33 patients) and 9.7% in the heparin group (31 patients) (p less than 0.01). These results suggest that low-dose heparin effectively prevents DVT after open prostatectomy
In a case of osteogenesis imperfecta with multiple fractures already from childhood, myelomatosis was diagnosed at the age of 52 years because of a serum M-component (IgG, lambda), Bence Jones proteinuria, myeloma cells in the bone marrow, and osteolytic skeletal lesions. She died 10 months later. A partial postmortem examination of a larger bone lesion confirmed the diagnosis.
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Bone mineralization is impaired in alcoholic non cirrhotics admitted to hospital for withdrawal. The defect is more marked in women than in men. Low 25-OH vitamin D plasma values may be observed in these patients and seem to be related to malnutrition. The degree of bone demineralization is not statistically correlated to 25-OH vitamin D plasma level.
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Thyroid investigations were performed on 55 euthyroid patients hospitalized for chronic disease or recovering from acute illness. Three age groups were considered. Abnormalities were found only in patients over 75 years: 1) in the TRH test the maximum increase in serum TSH (delta TSHmax) was less marked and frequently delayed to 60 min, whereas the increase in T3 in 120 min (delta T3) was maintained; basal TSH was normal; 2) in 15 out of 28 cases, the pattern of circulating thyronines was abnormal showing an increase in reverse T3 a normal or decreased T3, and a rise in free T4 index beyond the normal range in 3 cases. In all cases but one, the combination of delta TSHmax, and delta T3 differentiated these patients from hyperthyroids.
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