Biomedical subjects
B G Clarke
Publications and source records attributed to B G Clarke.
Cryoglobulinaemic neuropathy--a clinical spectrum.
In this report we present two cases who illustrate both ends of the spectrum of neuropathy with cryoglobulinaemia. Both patients responded well to treatment. A cryoglobulin assay should be done routinely in patients with mononeuritis multiplex of unknown cause, cutaneous vasculitis with cold sensitivity and chronic demyelinating neuropathies of unknown cause.
Lung mechanics after cardiac valve replacement.
Fourteen patients undergoing single aortic or mitral valve replacement had measurements made of lung volumes, static pressure-volume (P-V) relationships, and conductance-pressure relationships during deflation before operation and again between one and two years later. At follow-up, total lung capacity (TLC), functional residual capacity (FRC), residual volume (RV), and static tidal compliance (slope of static P-V deflation line for one litre above FRC) had increased significantly, in association with a decrease in heart size. There was a change in the shape and position of some P-V curves both in the aortic and mitral patients. In the patients with aortic disease P-V deflation curves shifted to the left after operation. In the patients with mitral disease the P-V deflation curves before operation crossed those measured after operation, so that at high lung volumes recoil became less after operation, but at low lung volumes recoil increased. Conductance had increased at high lung volumes. The data suggest that in longstanding pulmonary congestion, airways are more rigid making them less distensible at high and less compressible at low transpulmonary pressures than after operation when congestion has been at least partly relieved.
Intravenous co-trimoxazole therapy in serious infections.
The intravenous therapy with co-trimoxazole was used to control serious sepsis in 15 patients in the intensive care unit of a large metropolitan hospital. Co-trimoxazole was found to be a safe, effective, and eminently satisfactory alternative to the present vogue treatments of serious, bacteriologically undiagnosed infections.
Infection in the intensive care unit.
An epidemic of infection associated with Serratia marcescens and other Gram-negative organisms resistant to aminoglycosides and other chemotherapeutic agents occurred in the intensive care unit of St Vincent's Hospital, Melbourne, and spread to other areas of the hospital. This paper describes the problems of sepsis in the critically ill patient, outlines the occurrence of organisms in the patients concerned in this epidemic, and discusses the policies adopted to control the incidence of life-threatening infection caused by bacteria resistant to all other agents.
Changes in airways conductance on smoking a cigarette. A study of repeatability and of the effect of particulate and vapour phase filters.
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Relationship of pelvic bone fracture patterns to injuries of urethra and bladder.
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The relative frequency and age incidence of principal urological diseases.
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Urological aspects of Vietnam War injuries.
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Wounds and injuries of the kidney.
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Incidence of varicocele in normal men and among men of different ages.
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A simple technique for measuring changes in ventilatory response to carbon dioxide.
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Urology in hospitals of the United States and Canada, 1963 and 1964: report of a statistical study.
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