A rapid automatic analysis of hydroxylysine, hydroxylysine glycosides, and methionine sulfoxide in collagen and basement membrane.
Explore the source record for details and available documents.
Animals↗
Biomedical subjects
B G Hudson
Publications and source records attributed to B G Hudson.
Chemical and physical properties of serum transferrins from several species.
Explore the source record for details and available documents.
Amino Acids↗
Micro-chromatographic and radiochemical analysis of glycopeptides.
Explore the source record for details and available documents.
Chromatography, Gel↗
Studies on the native and reduced alkylated renal glomerular basement membrane. Solubility, subunit size, and reaction with cyanogen bromide.
Explore the source record for details and available documents.
Alkylation↗
Fractionation of glycoprotein components of the reduced alkylated renal glomerular basement membrane.
Explore the source record for details and available documents.
Alkylation↗
Enzymic synthesis of lactose- 14 C (galactosyl- 14 C) and lactose- 3 H (glucosyl- 3 H).
Explore the source record for details and available documents.
Animals↗
Separation of immunologically active fragments by membrane partition chromatography.
Explore the source record for details and available documents.
Animals↗
A modified ultrafiltration cell for separating the products of proteolysis.
Explore the source record for details and available documents.
Chromatography, Gel↗
Removal of low molecular weight contaminants from 131-I-labeled insulin by selective ultrafiltration.
Explore the source record for details and available documents.
Chromatography, Gel↗
Fractionation of protein solutions by membrane partition chromatography.
Explore the source record for details and available documents.
Albumins↗
The overoxidation of carbohydrates with sodium metaperiodate.
Explore the source record for details and available documents.
Oligosaccharides↗
Goodpasture syndrome: selective removal of anti-alpha 3 (IV) collagen autoantibodies. A potential therapeutic alternative to plasmapheresis.
Anti-alpha 3(IV) collagen autoantibodies have been implicated in the pathogenesis of Goodpasture syndrome, an autoimmune disorder causing glomerulonephritis and pulmonary hemorrhage. Currently treatment involves removal of the entire IgG fraction of plasma by plasmapheresis or adsorption to protein A. The present study shows that the anti-alpha 3(IV)NC1 autoantibodies can be removed from plasma specifically and quantitatively by affinity chromatography utilizing either alpha 3 NC1 domain of bovine type IV collagen or recombinant alpha 3 NC1 domain of human type IV collagen immobilized to agarose beads. This study shows the feasibility of using affinity chromatography, as an alternative to plasmapheresis, to exclusively remove the pathogenic autoantibodies from the plasma of patients with Goodpasture syndrome.
Adsorption↗