Biomedical subjects

B G Jacoby

Publications and source records attributed to B G Jacoby.

4 recordsLinked to original sources

PubMed1994

Cataract formation and cataract extraction after penetrating keratoplasty.

PURPOSE: This retrospective study was done to identify risk factors for cataract formation and cataract extraction after penetrating keratoplasty to determine whether a combined procedure (simultaneous cataract extraction with keratoplasty) or penetrating keratoplasty alone should be performed. METHODS: Variables from 342 phakic eyes having undergone penetrating keratoplasties were studied with univariate and multivariate analyses, including diagnosis, race, sex, age, preoperative lens opacities, preoperative vision, and length of follow-up. RESULTS: For cataract formation, age was the only independent risk factor found by multivariate analysis (P = 0.0001). For cataract extraction after penetrating keratoplasty, independent risk factors included age, sex, diagnosis, and preoperative lens opacities (P < or = 0.03). For example, the probability of a 65-year-old patient with Fuchs dystrophy requiring a cataract extraction within 5 years of keratoplasty is 81%. CONCLUSION: The likelihood of cataract formation and cataract extraction subsequent to penetrating keratoplasty increases greatly after 50 years of age, regardless of the diagnosis leading to the need for keratoplasty. The need for cataract extraction also is increased for female patients, for patients with Fuchs dystrophy, and for those with early preoperative lens opacity.

Adolescent↗

PubMed1992

Corneal epithelial basement membrane dystrophy: an overlooked cause of painless visual disturbances.

Although decreased vision from corneal epithelial basement membrane dystrophy (CEBMD) usually is associated with pain from corneal epithelial erosion, it may be an overlooked cause of painless, sometimes sudden, visual disturbance. We report a series of eight patients referred to our department with visual deficits for whom various diagnoses had been made. A total of 15 neurologic and ophthalmologic tests had been ordered before their referral. All patients had CEBMD as a cause for their visual deficit. Retroillumination through a dilated pupil and examination of the fluorescein tear film were the best methods to demonstrate the CEBMD. Six of the eight patients underwent epithelial debridement with complete resolution of their symptoms. We recommend that all patients with unexplained visual disturbances be examined closely for CEBMD.

Adult↗

PubMed1991

Ciliary sulcus anatomical dimensions.

Trans-scleral ciliary sulcus and iris suture fixation of posterior chamber intraocular lenses (IOLs) in eyes without posterior capsular support are techniques gaining wider acceptance. Primary indications are IOL exchange in pseudophakic bullous keratopathy and secondary IOL insertion in aphakia. Accurate placement of the posterior chamber lens loops within the ciliary sulcus is based on knowledge of ciliary sulcus anatomy. Nineteen postmortem eyes were sectioned in the coronal plane to expose the posterior iris border and the ciliary body. Ciliary sulcus diameters were measured, and the mean diameter was 11.0 +/- 0.37 mm. The mean limbus-ciliary sulcus distance was then measured by passing 26-gauge needles through the ciliary sulcus and sclera. The mean limbus-ciliary sulcus distance was 0.9 mm. These measurements may guide ophthalmic surgeons in choosing appropriate IOL designs for IOL exchange or secondary IOL procedures.

Ciliary Body↗

PubMed1987

Painful orbital inflammatory lesions and mastocytosis.

A 15-year-old female patient developed painful nodules in an anophthalmic socket that were exacerbated by treatment with steroids and narcotics. Although orbit biopsy showed chronic inflammation, the diagnosis of mastocytosis was confirmed with skin biopsy and urinary levels of histamine. The patient responded to excision of nodules and treatment for mastocytosis. Painful orbital lesions associated with mastocytosis have not been reported previously.

Adolescent↗