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Biomedical subjects

B G Lamberty

Publications and source records attributed to B G Lamberty.

At least 19 recordsLinked to original sources

Giant cell tumours in mandible and spine: a rare complication of Paget's disease of bone.

The case of a man who was diagnosed as having polyostotic Paget's disease at the age of 52 years is described. He developed a rare neoplastic complication of Paget's disease--a giant cell tumour in his mandible, which was excised. Nine years after the diagnosis of this tumour he developed a new giant cell tumour arising from the L3 vertebral body. He was born in Avellino in Italy, from where five other cases of giant cell tumours arising from Pagetic bone disease have been reported. No family relationship between our patient and the other cases was established. His Paget's disease was particularly aggressive and resistant to treatment with two single high dose infusions of pamidronate almost two years apart.

Aged

Fasciocutaneous flaps.

It is difficult to be objective about the fasciocutaneous system of flaps, whose development continues at an alarming speed. The references cited in this article, by no means comprehensive, are testimony to that. We have tried to be selective in our choice of reference, and anyone familiar with these references will have a good understanding of the fasciocutaneous system. These flaps have been recognized for less than 10 years, but their origins have been well based on an anatomical foundation. The revival in the anatomical basis of flaps, whether they be skin based, muscle based, or fascia based, is, we think, one of the most significant factors in the huge advance we have seen in reconstructive techniques in the last decade. To put reconstructive surgery in perspective, we see it in the following way: 1. Distant origins from ancient Egypt through Tagliacozzi to Dieffenbach. 2. The birth of modern reconstructive surgery, 1900 to 1930. 3. Skin flaps and the age of the tube, 1930 to 1960. 4. Anatomical renaissance; the axial skin flap and microsurgery. 5. The 1970s, decade of the muscle and musculocutaneous flaps. 6. The 1980s, decade of the fasciocutaneous flap. We repeat that to see our present efforts objectively is difficult. What is close to us seems more important, but as we progress further away from the origins of the fasciocutaneous flap, some aspects of these flaps will be seen as more important than others. The concept of including the fascia to produce a composite fascial skin flap is of fundamental importance. The discovery of these flaps is a milestone in reconstructive surgery. Our anatomical understanding of all flaps is also of paramount importance. Some of the individually described fasciocutaneous flaps will always remain best buys; some will be forgotten--and maybe even rediscovered.

Extremities

Cadaver studies of correlation between vessel size and anatomical territory of cutaneous supply.

The anatomical territories of individual vessels supplying the skin and subcutaneous tissues have been measured in specimens of cadaver skin following intra-arterial whole-body barium sulphate injection. An attempt has been made to correlate these area measurements with measurements of the diameters of individual vessels. A method has also been devised for measuring the "axiality" of the territories of distribution of individual perforators.

Blood Vessels

The blood supply of the bone component of the compound osteo-cutaneous radial artery forearm flap--an anatomical study.

This paper reports the results of an investigation into the blood supply of that portion of the distal radius which may be incorporated into the fasciocutaneous radial artery forearm flap. The findings demonstrate that when detached from its medullary blood supply, this segment of bone is supplied predominantly by two fascioperiosteal branches of the radial artery augmented by a musculoperiosteal plexus at the site of attachment of flexor pollicis longus.

Adult

Small cell carcinoma of skin: a report of two cases.

We present two cases of small cell carcinoma of skin and review the evidence for the origin of these tumours from Merkel cells situated in the basal layers of the epidermis. The aggressive behaviour of these tumours makes their initial histological diagnosis important if careful follow-up is to be instituted and we suggest that more radical primary treatment might improve results. We emphasise the need to exclude an origin from other sites apart from skin and the role of electron microscopy and immunohistochemistry in identifying these tumours as being distinct from other poorly differentiated carcinomas.

Aged

Transcutaneous oxygen tension as an index of maturity in hypertrophic scars treated by compression.

Sixteen patients undergoing compression treatment for scar hypertrophy were included in a study to evaluate physical indices of scar maturity. The results show that while thermographic measurements of scar temperature were not clinically valuable, rising levels of transcutaneous oxygen tension in treated scars correlated well with a reduction in scar thickness assessed both clinically and by ultrasound. It is postulated that low levels of tcpO2 in immature scars result from low oxygen diffusibility through scar tissue rather than from rapid metabolic consumption of oxygen by scar tissue.

Adolescent

The blood supply of thigh skin.

The pattern of blood supply to the integument of the thigh is reported. A new technique is described for analyzing the length, direction, and number of arterioles in specimens of cadaver skin and deep fascia. The information obtained from these studies adds to existing knowledge of the anatomic vascular basis of direct cutaneous and musculocutaneous flaps in this region and provides a scientific basis for the elevation of fasciocutaneous flaps in such a way as to aid the achievement of maximum length-to-breadth ratios.

Fascia

Fasciocutaneous vessels. Their distribution on the trunk and limbs, and their clinical application in tissue transfer.

In the conventional view of the arterial blood supply of skin, two systems of vessels are recognised; the direct cutaneous arteries and the musculocutaneous perforators. The existence of a third system consisting of fasciocutaneous perforators, is a relatively new concept. These vessels supply the skin by passing along the fascial septa between adjacent muscles. A particular feature of these fasciocutaneous perforators is that they spread out at the level of the deep fascia, forming a fascial plexus which often has a marked directionality. The locations of these perforators and the axiality of the fascial plexi are described. This knowledge is important for the elevation of pedicled fasciocutaneous flaps and the design of fasciocutaneous microvascular free tissue transfers.

Arm

Fasciocutaneous vessels in the upper arm: application to the design of new fasciocutaneous flaps.

The principles of the blood supply to the upper arm are described. Despite the large, fleshy nature of the biceps and the triceps, the blood supply to upper arm skin is not from the underlying muscles, but is by fasciocutaneous perforators emerging along the medial and lateral intermuscular septa. Fifty dissections of preserved cadavers have shown that on the lateral side the fasciocutaneous perforators consistently arise from the middle collateral artery. The available length of this vessel and its diameter have been measured and are reported. The design of a flap based on this vessel, in a manner analogous to the Chinese forearm flap on the radial artery, is described.

Arm

Misconceptions regarding the cervico-humeral flap.

Various authors have reported different failure rates for the cervico-humeral flap. An attempt is made to explain these occurrences in the light of recent experimental and clinical work which has increased our knowledge of the detailed blood supply of the supraclavicular fossa and shoulder region. In particular, the role of a fascio-cutaneous vessel in the supply of a proximally based shoulder flap is stressed. Division of this vessel may occur during proximal mobilisation of the cervico-humeral flap. This fundamentally alters the nature of the flap and may be the key to the varying failure rates. The implications of this for fascio-cutaneous flaps in general are discussed.

Humans

The anatomical vascular basis of the axillary fascio-cutaneous pedicled flap.

The reliability of the axillary fascio-cutaneous flap recently described in this Journal was attributed to the presence of vessels in a fascial plexus. This paper describes the findings in anatomical studies of the vasculature in this region and highlights an important directional component in the fascial plexus at this site. Comparisons are made with other regions of the posterior trunk and the implications for pedicled fascio-cutaneous flaps elsewhere are discussed.

Axilla