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Biomedical subjects

B G Watson

Publications and source records attributed to B G Watson.

9 recordsLinked to original sources
PubMed1986

Diabetes mellitus and open heart surgery. A simple, practical closed-loop insulin infusion system for blood glucose control.

A method, based on bedside determinations of blood glucose by nursing staff, was designed to control the administration of insulin to diabetic patients during and following open heart surgery. A computer-controlled intravenous infusion pump was used to deliver the insulin. Excellent control of the hyperglycaemia normally associated with open heart surgery was achieved, with 84 percent of measured blood glucose values falling within 2 mmol/litre of the target value of 6 mmol/litre. The method proved to be simple, effective, and safe.

Adult↗
PubMed1985

Practical closed-loop insulin infusion.

A method was designed to control the insulin infusion given to diabetic patients at the time of open-heart surgery. Excellent control of the blood glucose concentration was achieved, with eighty-four percent of blood glucose values falling between 4 and 8 mmol/l.

Adult↗
PubMed1983

Unilateral cold neck. A new sign of misplacement of the aortic cannula during cardiopulmonary bypass.

A case is reported of survival following accidental cannulation of the innominate artery during cardiopulmonary bypass. Coldness of the right side of the neck was noticed during cooling of the patient and is a useful new sign of misplacement of the aortic cannula. Confirmation of miscannulation of first the innominate then the left common carotid artery was obtained by palpation of the neck pulses during total cardiopulmonary bypass using a pulsatile pump.

Aorta↗
PubMed1978

An ultrasonic analysis of the comparative efficiency of various cardiotomy reservoirs and micropore blood filters.

The ability of 12 commercially available cardiotomy reservoirs to remove bubbles from aspirated blood was investigated by means of a simulated cardiopulmonary bypass circuit and an ultrasonic microbubble detector. Performance varied considerably. The number of gaseous microemboli remaining after passage of blood through the reservoir was reduced by (a) holding the blood in the reservoir, (b) reducing the volume of air mixed with the aspirated blood, and (c) using a reservoir that did not induce turbulence and that contained integral micropore filtration material. Further micropore filtration of the blood after passage through the cardiotomy reservoir was beneficial, and significantly more bubbles were extracted when the microfilter was sited below the reservoir than when it was placed in the arterial line.

Cardiopulmonary Bypass↗
PubMed1977

Prevention of venous blood gas embolism with blood microfilters.

The efficacy of blood microfilters in removal of the gaseous emboli produced during the warming of blood for transfusion is demonstrated experimentally. It is suggested that when blood microfilters are used they should be placed distal to any blood warming device.

Blood Transfusion↗
PubMedDate not supplied

A system for peri-operative blood glucose control in diabetes mellitus.

A pocket computer has been programmed to control the rate of administration of insulin given to diabetic patients having open heart surgery. Twelve diabetic patients were studied. Five had coronary artery bypass grafting, and seven had heart valve surgery. During operation 122 out of 162 (75%), and post-operatively 291 out of 360 (81%) blood glucose concentrations were between 4.0 and 8.0 mmol l-1. Five hundred and fifteen values out of 552 (99%) were below 12.0 mmol l-1. There was no hypoglycaemia. The lowest measured blood glucose concentration was 3.7 mmol l-1. The computer is readily available, easy to use by inexperienced personnel, and cheap.

Adult↗