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Biomedical subjects

B Garcia-Bravo

Publications and source records attributed to B Garcia-Bravo.

11 recordsLinked to original sources

Two cases of contact dermatitis caused by calcipotriol cream.

Two patients with psoriasis were treated with calcipotriol cream, and both developed contact dermatitis. Patch test results were positive to calcipotriol and negative to the ingredients of the vehicle in both cases. The first case may be explained by a compound allergy or by a false-negative reaction to calcipotriol due to the very low concentration used for patch tests. The second patient was clearly positive to calcipotriol despite low concentration. This is the first case reported thus far with sensitivity to calcipotriol at a concentration < 2 mc/mL, as recommended in other studies.

Administration, Topical↗

[Incontinentia pigmenti. Study of 3 families].

Ten cases of incontinentia pigmenti are reported. All patients, corresponding to three families, were female. In one case a Turner's syndrome phenotype (XO) with mosaicism 46 XX/46 X; i (Xq) was observed. This finding seems to confirm that the disease is transmitted through a dominant gene carried on the X chromosome. Dental alterations were the most frequent of associated abnormalities, being present in all 10 patients. We regard these abnormalities as important as they permit a retrospective diagnosis in adult patients after the skin lesions have disappeared. EEG alterations (essentially an increase in the slow component) were also observed in the majority of cases.

Adolescent↗

Standard patch tests in agricultural workers.

The results obtained with a standard patch test series in a group of agricultural workers is compared with a control group. Statistically significant differences in the frequency of several allergens were found. The possible causes of these differences are discussed.

Agricultural Workers' Diseases↗