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Biomedical subjects

B Goetze

Publications and source records attributed to B Goetze.

7 recordsLinked to original sources
PubMed1993

[A rare metastatic manifestation of vulvar cancer--a case report].

A case of a solitary metastasis of a vulvar carcinoma we describe in the present paper. Anamnestic, a radical laser-vulvectomy with bilateral lymphonodectomy in 1986 (5 years ago) was carried out on account of a well differentiated squamous cell carcinoma (pT2 pN1 MX). The localization of this metastasis and the speed of progression under radiation therapy was very unusual.

Aged↗
PubMed1992

[Use of xylocaine in placing afterloading applicators in the gynecologic area--a simplified and analgesic method].

The afterloading contact therapy is an established method in the therapy strategies of extended gynecological malignancies. Unfortunately, the manipulations of application are painful in many cases. The results of the present paper suggests, that the pretherapeutic application of Lidocain (Xylocain) may decrease in pain symptomatic significantly. This findings have relevance for ambulant afterloading contact therapy.

Anesthesia, Local↗
PubMed1990

Decreased adherence, chemotaxis and phagocytic activities of neutrophils from preterm neonates.

Using microanalytic assays various phagocytic functions of separated neutrophils from preterm neonates (mean birthweight 1,506 g, n = 13) were simultaneously studied. Adherence of neutrophils to nylon fibre was decreased in cells from preterm infants (77.1 +/- 3.1%) when compared with adult controls (86.9 +/- 2.1%, mean +/- 1 SD, p less than 0.05). In addition neutrophil chemotaxis in response to zymosan activated serum was reduced in preterm neonates (131.9 +/- 19.7, adults 166.6 +/- 11.1, p less than 0.001); directed migration towards Formyl-Methionyl-Leucyl-Phenylalanine was also decreased (preterm neonates 93.4 +/- 15, adults 111.1 +/- 16.8, p less than 0.05). Preterm infants had a higher percentage of slow moving neutrophils when compared with adults (p less than 0.001). Phagocytosis of Candida albicans was reduced in neutrophils from preterm neonates (phagocytic index: preterm neonates 41.4 +/- 12.7, adults 83 +/- 7.2). Adult neutrophils ingested more Candida per cell (p less than 0.001). Chemiluminescence, exocytosis of elastase and lactoferrin during uptake of opsonized zymosan was also reduced in neutrophils from preterm neonates. However, random migration, phagocytosis of Staphylococcus aureus and production of O2- in response to Phorbol myristate acetate or opsonized zymosan were identical in cells from either source. We conclude, that these abnormalities of neutrophils could predispose the preterm infant to serious and often overwhelming bacterial and fungal infections.

Adult↗
PubMed1985

[Clinical aspects and results of therapy of endometrial cancer at the Department of Medicine of the Friedrich Schiller University in Jena 1964-76. II: Results of primary radiotherapy].

In this paper results of irradiation only at 235 patients are reported and discussed, different treatment methods are applicated. The 5-year-survival rate of all cases amounted 35.7 per cent, the rate of complications 6.2 per cent. Measures of improvement of therapeutic results are investigated.

Adenocarcinoma↗
PubMed1985

[Clinical aspects and results of therapy in endometrial cancer at the Department of Medicine of the Friedrich Schiller University in Jena 1964-76. I: Evaluation of primarily surgically treated endometrium cancer].

In this paper therapeutic results are reported obtained from 444 patients with endometrial cancer which were operated on. In 260 patients the primary operation was completed by a different radiation therapy. The 5-years-survival rates are 75,9% Surgical and radiological therapeutic measures are demonstrated with regard to their development and to side effects.

Adenocarcinoma↗