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B Golosio

Publications and source records attributed to B Golosio.

2 recordsLinked to original sources

A new algorithm for computer tomographic reconstruction from partial view projections.

Conventional algorithms for tomographic reconstruction require the acquisition of a complete set of projections at uniform angular displacements. In many cases, however, the geometry of the sample or a loss of data can significantly reduce the range of the available projections. Several algorithms have been proposed in literature to handle such situations, but their performances are low or they require strong constraints and hypothesis about the nature of the sample or the data. Here a new method is proposed. It is based on a novel morphing technique, which affords in general terms the problem of curve matching and is here specialized to the case of tomographic reconstruction. The proposed algorithm is very fast in comparison to other approaches having similar effectiveness; furthermore, it allows one to obtain good quality images even when a significant fraction of the views is absent, without any hypothesis about the nature of the sample or the kind of measurement. The results obtained by applying this technique to the Shepp-Logan phantom and to a clinical scan are reported here and discussed.

Algorithms↗

A real-time classification system of thalassemic pathologies based on artificial neural networks.

Thalassemias are pathologies that derive from genetic defects of the globin genes. The most common defects among the population affect the genes that are involved in the synthesis of alpha and beta chains. The main aspects of these pathologies are well explained from a biochemical and genetic point of view. The diagnosis is fundamentally based on hematologic and genetic tests. A genetic analysis is particularly important to determine the carriers of alpha-thalassemia, whose identification by means of the hematologic parameters is more difficult in comparison with heterozygotes for alpha-thalassemia. This work investigates the use of artificial neural networks (ANNs) for the classification of thalassemic pathologies using the hematologic parameters resulting from hemochromocytometric analysis only. Different combinations of ANNs are reported, which allow thalassemia carriers to be discriminated from normals with 94% classification accuracy, 92% sensitivity, and 95% specificity. On the basis of these results, an automated system that allows real-time support for diagnoses is proposed. The automated system interfaces a hemochromo analyzer to a simple PC.

Adolescent↗