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Biomedical subjects

B Golse

Publications and source records attributed to B Golse.

At least 19 recordsLinked to original sources

[Is the concept of resilience useful or suitable?].

Having reminded various models of the concept of resilience, the author investigates this concept towards the psychoanalysis (via the concepts of maternal dreaming capacity, psychic bisexuality and malleability), and the attachment theory. Whatever is the theory to which we refer, two questions raise: what is the genetic part of the part acquired in utero of resilience, and what is the part able to report interpersonal differences.

Adaptation, Psychological↗

Validation of the Edinburgh postnatal depression scale (EPDS) in a sample of women with high-risk pregnancies in France.

UNLABELLED: This research is intended to validate the Edinburgh Postnatal Depression Scale (EPDS) in a high-risk pregnant population. METHOD: Sixty women attending antenatal consultations for pregnancy complication in a major Parisian maternity facility were included. They completed the EPDS and were then interviewed according to a standardised psychiatric interview. RESULTS: The study of its sensitivity, specificity and predictive values, with a DSM-IV diagnosis of major depression as the reference, found that 11.5 was the optimal cut-off score (Se 0.80; Sp 0.80). Its validity as an index of severity of depression was also good as well as internal consistency and reliability. Factor analysis showed that its internal structure is composed of two subscales (F2 "depression" and F1 with items reflecting depression and other disorders, including anxiety). CONCLUSION: The French version of the EPDS would be a valid instrument to identify pregnant women who are likely to have clinical major depression. The results may have to be confirmed on a community sample before clinical use.

Adult↗

[Hyperactivity in infants below the age of six].

"Attention deficit with hyperactivity disorder" is a syndrome very difficult to detect at the earlier age of the life,before 3 or 4 years. Early signs are aspecific and the impact of the syndrome on socio-scolar adaptation is only detectable later on. So, the proto-syndrome is still discussed. It seems really important to face this problem in a polyfactorial perspective and in the light of child's history, because the signification and the meaning of the troubles are the key of the therapeutical choice which is not reducible only to amphetamine-like treatment.

Age Factors↗

The pediatric team and the consulting child psychiatrist and the hospitalized depressed infant.

The link between pediatricians and child mental health professionals is a complex, but fascinating issue. Based on our clinical experience, this paper will discuss the issue of depression in very young children hospitalized for serious illness in a general pediatric ward, and its theoretical implications. We begin with a clinical vignette, followed by a review of several clinical phenomena including anticipated bereavement (either by the parents or the medical team, or both), some high-tech medical conditions specific to neonatology and joint parents-infant hospitalization as well as relating the above to psychoanalytical concepts. The significance and importance of adopting a dual perspective, from both the pediatric and the psychopathological viewpoint, while treating the very sick hospitalized young child and his/her parents, is underlined.

Adjustment Disorders↗

[Infantile autism in France in 1994].

The author tries, in is own, name to translate the French position on early child autism. This position can be expressed through a few acceptable points for the majority of French professionals, obviously without any idea of a consensus. The concept of a plurifactorial determinism and the psychopathological view of the disorder which is not thought of in France as susceptible to be reduced to a handicap of a primarily cognitive nature are therefore underlined. Thus the importance of a unified multidimensional therapeutic approach that considers the different consequences of the illness without forgetting its fundamentally interactive nature ("autistic-making process"). Today, the psychoanalytic approach tends to concentrate on the analysis of secondary factors of upholding and on the significance given in the after-thought by the autistic disorders within the family group. This opens the way to a collaboration between specialists of the different disciplines that are involved, including those who work in the field of neuroscience.

Autistic Disorder↗

[Nightmares--dreams and thought processes].

After reviewing the literature concerned with the function of dreaming and especially dreaming in the child, the author presents various theories about the role of dream, with special emphasis on S. R. Palombo's theory on the relationships between dream and memory. The proposed hypothesis, which is based on various elements (as study of nightmares in children, oniric life of pregnant or post-partum women, occurrence of nightmares in autistic children and counter-transferential drowsiness in the analyst) takes nightmares as a more or less complete failure of the primarization processes of primary significants. The issue of dreams and nightmares is being related here with the now classical distinction of psychic processes in originary, primary and secondary ones. To be sure, this is but a mere metapsychological hypothesis which needs to be developed by further clinical studies.

Adult↗

[Infantile autism, psychoanalytic research and scientific status].

After emphasizing the very modern aspect of psychoanalytic epistemology, the author shows how psychoanalytical research applied to the issue of infantile autism concentrates the maximum of difficulties and is therefore vulnerable to critics from the "hard" sciences. Some tentative answers are proposed in reference to the narrative sciences. The author then suggests various tracks for the psychoanalytical research in the field of infantile autism.

Autistic Disorder↗

[The autistic child, his thoughts, his body and his images. Or the footprint of a step not yet taken].

The author studies the autistic mind through the concept of image. This concept is differentiated from the processes of representing (and mainly self-representation), figuration and communication. The author then discusses different aspects of the image: mental image, mirror image and physical image. Finally is discussed the narcissistic or objectal polarity of image production in the autistic child and the author argues that in these cases the transformation from the original to the primary level is essentially disturbed.

Art Therapy↗

[Psychogenic growth retardation. Critical study of diagnostic data].

The diagnosis of psychosocial deprivation dwarfism is difficult. It is also of practical importance since it leads to the only one appropriate treatment: the decision to send the child in a new environment, foster institution or foster family. The present work reports the clinical, biological and psychologic characteristics of 34 children and adolescents aged 9 months to 17 years, in whom a severe growth deficiency had been considered as probably related to psychosocial deprivation, and who were thus sent in foster institutions with good medical and psychological support. The result was in 24 cases a sharp increase of growth rate, giving confirmation of the diagnosis suspected, and in 10 a failure, making this diagnosis unlikely. A comparison of these two groups does not demonstrate any significantly different criterion. The conclusion suggested is thus the following: a trial of at least three months in a foster home, decided on concordant clinical and psychological data, without regard to the biological data, is the only way for distinguishing the truly and falsely deprivation-related dwarfism, or at least to give appropriate support for long-term therapeutic decisions.

Adolescent↗

[Ambulatory treatment of diabetes in children by continuous subcutaneous infusion of insulin using a portable pump].

Six diabetic children, aged 2 to 4 years, were selected for continuous subcutaneous insulin infusion (SCII) therapy using a portable pump, because of unstable glycemic control. Under previous conventional insulin therapy, they experienced both chronic hyperglycemia (mean: 2.10 +/- 0.07 milligrams, HbA1 C: 9.02 +/- 0.2%) and frequent or severe hypoglycemic manifestations. Reduction of both glycemic level: 1.08 +/- 0.04 milligrams (p less than 0.01) and instability: M index 0.76 +/- 0.2 vs 5.5 +/- 1.4 (p less than 0.01) was obtained the first week after CSII therapy was started. The metabolic improvement was maintained over 5 to 9 months of ambulatory CSII therapy: HbA1 C decreased down to 7.6 +/- 0.6% (p less than 0.05), while hypoglycemic episodes became rare. The portable insulin delivery system was well tolerated both physically and psychologically by 5/6 of the children and their families.

Blood Glucose↗

[Alterations in two enzymes: superoxide dismutase and glutathion peroxidase in developmental infantile psychosis (infantile autism) (author's transl)].

After they gave a classification of the different circumstances under which the infantile autism can exist, the authors expose the data of their researches on the intermediate metabolism of oxygen of those children. Superoxyde dismutase I and glutathion peroxydase activities seem to be abnormal in the erythrocytes whereas only superoxyde dismutase I activity appears to be abnormal in the platelets.

Adolescent↗

[HLA groups in the infantile psychoses during development, and hypothesis for an enzyme defect].

The HLA typing (loci A and B) of a series of fifteen psychotic children has shown an increase of the frequency of both HLA-A9 and B5 antigens. These preliminary data and previous biochemical findings in psychotic patients lead the authors to postulate the hypothesis of a qualitative or quantitative anomaly of the superoxide dismutase (SOD-2), the gene of which is situated on the same chromosome (sixth) as the HLA complex.

Child Development↗