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Biomedical subjects

B Grigsby

Publications and source records attributed to B Grigsby.

7 recordsLinked to original sources
PubMed1994

Growth-inhibitory effect of pyrophosphate on oral bacteria.

The purpose of this investigation was to determine whether pyrophosphate, the anticalculus component of tartar-control dentifrices, exerts antimicrobial activity against oral bacteria commonly found in supragingival plaque. Minimal inhibitory concentrations of pyrophosphate were determined for Streptococcus sanguis, Streptococcus mutans (serotype c), Actinomyces viscosus and Actinomyces naeslundii. All of the bacteria tested were susceptible to pyrophosphate with identical minimal inhibitory concentrations of 0.67% wt/vol (25 mM). Bactericidal kinetics assays revealed that both S. mutans and A. viscosus were killed by pyrophosphate, with the latter being considerably more susceptible. The mechanism of killing was not due to high ionic strength, as comparable controls showed no loss in numbers of viable cells. Brief exposure (two 5-min incubations) of S. mutans to pyrophosphate and sodium dodecyl sulfate caused pronounced inhibition of growth over the 24-h test period. Under the constraints of the conditions used, these studies indicate that pyrophosphate and sodium dodecyl sulfate can substantially inhibit the growth of oral bacteria. These compounds may affect the oral microflora of patients who routinely use tartar-control dentifrices and mouthrinses.

Actinomyces↗
PubMedDate not supplied

Telemedicine equipment and vendors: the users' perspectives.

The ATSP (Association of Telemedicine Service Providers) supplies current and future telemedicine providers with practical information and other services. One way to obtain useful data is to conduct focused studies on important issues. This ATSP survey of vendor and equipment satisfaction is a collaborative effort between the Telemedicine Research Center and the ATSP research staff, and addresses some basic questions that telemedicine providers might have: What kinds of equipment are programs using? Who is providing this equipment? How do users rate the equipment and the vendors? The results will be periodically updated and made available to members in the members-only section of the ATSP website (www.atsp.org).

Consumer Behavior↗