Biomedical subjects
Publications and source records attributed to B Grotelüschen.
Partial liver resections were carried out in pigs with a high power Neodym-YAG-laser. By variation of beam parameters different cutting characteristics were obtained and discussed.
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A new pattern of intensity distribution of laser beam, in the shape of a "topfkuchen" was found to be satisfactory in avoiding perforation when applied to the gastrointestinal tract. Basic data of the optical and thermophysical properties of the different layers in the stomach of pigs were obtained. Using our distribution pattern of intensity we could see a uniform, superficial zone of coagulation. There were no perforations even after the intact mucosa of the stomach was irradiated by 175 Watts for 2 seconds.
The suitability of the laser for use in surgery is discussed. The mode of action as well as the advantages and disadvantages of electro-cautery are described together with a discussion about the use of the laser as an alternative. After preliminary remarks about the physical aspects, the effects of laser rays on biological tissue are illustrated and the most important properties of the laser with regard to its use in surgery are pointed out. An outline is given of the present use of the laser in the experimental and clinical areas; the properties required of a cutting instrument in surgery are listed. Finally the influence of the rays on the cutting characteristics of a Nd-high-power-laser is investigated in experiments using a rat liver model. This laser has substantial advantages over the CO2-laser in its practical application. The cutting mechanism and the development of the necrotic areas are discussed, together with a description of the cessation of hemorrhage and wound healing. The results obtained indicate that as soon as technical problems can be solved, the use of a pulsed high power YAG laser as a cutting instrument in surgery is highly promising.
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A q-switched YAG-laser has been investigated as an "optical knife". It was possible to cut rat liver without bleeding but there was no influence of the repetition frequency on the cutting effect. Otherwise, the width of the necrotic zone could be changed evidently more by using the q-switch-technique than by using a cw-laser. First experiments with pig liver showed, that larger vessels can be cut without bleeding by using laser beams as an "optical tool".
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Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.