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B H Mock

Publications and source records attributed to B H Mock.

25 records · Page 2Linked to original sources
PubMed1985

Comparison of technetium-99m sulfur colloid and in vitro labeled technetium-99m RBCs in the detection of gastrointestinal bleeding.

Twenty-seven paired Tc-99m sulfur colloid (SC) and Tc-99m RBC studies were evaluated for the detection of GI bleeding. The only two positive Tc-99m SC studies had positive early Tc-99m RBC studies as well. There were 15 other positive Tc-99m RBC studies (three during the first hour) and these were associated with normal Tc-99m SC scans. Approximately 70% of the positive Tc-99m RBC studies occurred after 1 hour. Tc-99m RBCs should be the initial test in patients with GI bleeding.

Adolescent↗
PubMed1984

In-111 granulocyte response to intervening surgery. Evidence of sustained in vivo viability.

A patient with chronic osteomyelitis had surgery performed between the early and delayed images of an In-111 granulocyte scan. The early images showed no uptake, while the delayed images demonstrated marked soft tissue uptake, which was felt to be secondary to the inflammation of the intervening surgery. It was concluded that granulocytes, when labeled with In-111, remain viable and can respond to inflammation that occurs after their injection.

Adult↗
PubMed1984

Evaluation of complicating osteomyelitis with Tc-99m MDP, In-111 granulocytes, and Ga-67 citrate.

Studies with gallium-67 and three-phase bone imaging (TPBS), though very sensitive, are not very specific in evaluating suspected osteomyelitis (OM) that is superimposed upon other diseases causing increased bone turnover. A total of 57 patients with suspected OM were studied; this included 48 with increased bone turnover. All of the patients were studied with granulocytes labeled with In-111 acetylacetone (In-111 GRAN), TPBS and 29 of these patients had Ga-67 studies as well. In-111 GRAN had a sensitivity of 100% in acute OM and 60% in chronic OM, with a specificity of 96%. Gallium-67 was excellent in ruling out OM when the study was normal, or in ruling in OM when the relative uptake of Ga-67 exceeded the uptake of Tc-99m MDP, or when the Ga-67 in bone had a different distribution from the TPBS. Unfortunately, these criteria were met in only 28% of our subjects. We conclude that when added to TPBS, the In-111 GRAN study plays an important role in detecting complicating OM.

Acute Disease↗
PubMed1984

Stoichiometric Tc-99m RBC labeling using stable kit solutions of stannous chloride and EDTA: concise communication.

An in vitro Tc-99m labeling method is described, which utilizes stable stock solutions of stannous chloride and disodium edetate (EDTA). The kit procedure requires as little as 1 ml of patient blood, can be performed in only 15 min, and gives labeling yields in excess of 98%. By using EDTA, the binding capacity of RBCs for technetium is sufficient to produce Tc-99m RBC doses with specific concentration greater than 50 mCi/ml for first-pass cardiac studies. Scintigrams reveal a slight amount of bladder activity and splenic uptake, but at no time has the thyroid, stomach, or normal bowel been visualized. The predominant 20-hr blood-clearance half-time results in excellent image quality for over 24 hr--an essential property for following intermittent GI bleeding or for performing repeat cardiac function studies over a several-hour time interval.

Edetic Acid↗