Further studies on the hormone secretion of the anterior pituitary transplanted into the hypophysiotrophic area of the rat hypothalamus.
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Adrenal Glands↗
Biomedical subjects
B Halász
Publications and source records attributed to B Halász.
Hormone secretion of the anterior pituitary gland after physical interruption of all nervous pathways to the hypophysiotrophic area.
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Adrenal Glands↗
Effect of simultaneous local injection of 6-hydroxydopamine and naloxone on the testis of neonatal rats.
The effect of simultaneous intratesticular injection of the opiate receptor antagonist naloxone and the neurotoxic drug 6-hydroxydopamine (6-OHDA) on testicular growth, compensatory testicular hypertrophy, serum testosterone level and basal testosterone secretion in vitro was studied in neonatal rats. In animals with two testes unilateral intratesticular administration of naloxone alone enhanced, while 6-OHDA alone decreased the weight of the treated gonad. In animals treated simultaneously with these two agents the decrease in testicular weight induced by 6-OHDA was partially prevented by naloxone. In hemicastrated animals intratesticular treatment with naloxone enhanced the extent of compensatory testicular hypertrophy. Treatment of the remaining testis with 6-OHDA + naloxone did not interfere with the diminished compensatory testicular hypertrophy observed following 6-OHDA treatment. Data indicate that naloxone can counteract the degenerative effect of 6-OHDA in animals with two testes but not in hemicastrates.
Animals↗
[Permeability of the csf-brain barrier in the median eminence of rats in the perinatal period].
The ultrastructure and permeability of the CSF-brain barrier in the median eminence were studied during the perinatal period in rats with electron microscopy, electron-microscopic radioautography and electron-dense markers. It was shown that the ependymal cells forming the ventral portion of the 3rd ventricle (infundibular recess) are joined by the specialized junctions. The specialized junctions are similar in ultrastructure in different parts of infundibular recess all through the perinatal period. They consist of the tight junctions which are sometimes in series with the gap junctions and adhesion zones. An electron-dense marker, La3+, injected into the cerebral ventricles, penetrates through the foetal ependymal linins both via the ependymal cells and intercellularly in all parts of the infundibular recess. In neonatal rats La3+ penetrates in the same way in the rostral part of infundibular recess only, while in the caudal part its permeability is markedly limited, apparently by the tight junctions formed de novo around the cells. 3H-dopamine, introduced into the ventricles, crosses over the ependymal linins apparently in the same way as La3+. Then the labeled dopamine is transported into the pericapillary space of the primary portal plexus and, finally, into the capillary lumen. Thus, the results obtained point to the permeability of the CSF-brain barrier in the foetal median eminence for the markers including neurohormones. In the postnatal period the permeability of the ependyma becomes limited due to the formation of the tight junctions surrounding the ependymal cells.
Animals↗