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Biomedical subjects

B Hamza

Publications and source records attributed to B Hamza.

At least 37 records · Page 2Linked to original sources
PubMedDate not supplied

Seroimmunity following vaccination in infants by an inactivated poliovirus vaccine prepared on Vero cells.

An inactivated poliovirus vaccine prepared from cultures of Vero cells has been tested on 61 infants from two to 11 months of age (mean age, 4.3 months) for tolerance and serologic potency. Three doses of vaccine were given one month apart at the same time that diphtheria-tetanus-pertussis vaccine was injected at another body site. Poliovirus-neutralizing antibody titers were measured before the first and third injections and one month after each. The titer was considered positive when the dilution was greater than or equal to 1:4. The tolerance has been good. Thirty-one infants were assessable for serologic efficacy; all had significant serologic responses after two injections of polio vaccine, regardless of the titer of maternally transmitted antibodies before the immunizations. The third injection did not significantly increase the antibody titer observed after the first two doses.

Animals↗
PubMedDate not supplied

[Bilateral testicular hypertrophy and congenital adrenal hyperplasia caused by 11-beta-hydroxylase deficiency].

This study reports the case of a 5 1/2 year-old boy with congenital adrenal hyperplasia (11-beta-hydroxylase deficiency) and bilateral testicular hypertrophy. Microscopic and ultrastructural examinations did not show any nodular tumor or crystalloids or Reinke. However, interstitial cell hyperplasia was present which may have resulted in testicular enlargement. The patient had a younger brother also presenting with 11-beta-hydroxylase deficiency but with bilateral cryptorchidism. This suggests that ACTH hypersecretion alone is unlikely to be responsible for testicular enlargement.

Adrenal Hyperplasia, Congenital↗
PubMedDate not supplied

[Delayed hemorrhagic syndrome caused by hypovitaminosis K].

The authors describe two cases of delayed haemorrhagic disease by vitamin K deficiency, occurring at 28 days and 2 months 1/2 of age. The first case was revealed by an hematoma in the thoracic wall and anemia, and the second by convulsions caused by meningeal hemorrhage. The study of hemostasis and the correction of prothrombin rate after vitamin K injection show that it is a delayed haemorrhagic disease caused by vitamin K deficiency. Etiologic factors of this affection are discussed. The authors insist on the preventive role of the vitamin K injection in infants fed exclusively at breast and presenting diarrhea.

Female↗