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Biomedical subjects

B Hauser

Publications and source records attributed to B Hauser.

At least 91 records · Page 5Linked to original sources

Effect of a whey hydrolysate prophylaxis of atopic disease.

The incidence of atopic manifestations was analyzed in infants "at risk" because of histories of atopy in first degree relatives. The incidence of atopic manifestations was significantly reduced (P = .0011) during the first 6 months of life when only the whey hydrolysate was administered (2/32 infants, 6.3%) compared with the incidence when an adapted formula was given (14/35 infants, 40%). This beneficial effect continued during the 6 to 12-month period, after diversification of the diet at 6 months. At the age of 1 year, 7/32 (21.8%) of the infants in the whey hydrolysate group had presented with manifestations of probable atopic disease compared with 17/35 (48.6%) infants in the adapted formula group (P = .021). The incidence of cow milk protein sensitivity was evaluated at 5/32 (15.6%) in the hydrolysate group and 15/35 (42.8%) in the adapted formula group (P = .014). Other foods such as egg and fish may be responsible for manifestations in three infants in hydrolysate group and in five infants of the adapted group (9.4% and 14.3%, respectively NS). These preliminary data show that the administration of a whey hydrolysate during the first 6 months of life to babies "at risk" decreased the incidence of atopic disease up to the age of 12 months. The incidence of cow milk protein sensitivity appeared to be decreased, whereas the incidence of sensitivities to other food proteins was comparable in both groups.

Food Hypersensitivity↗

[Relation of visual acuity of test field luminance in glare sensitivity of various origin].

Intolerance to bright light is a nonspecific ophthalmological symptom, originating either in disturbances of the optic apparatus of the eye or caused by functional disturbances of the neuronal network of the retina. Disturbances in brightness and darkness adaptation can often cause considerable decrease in visual acuity, which is not evident in the standardized tests that measure photophobia in conjunction with visual function. If the test field is very bright and the patient has photophobia, the visual acuity is often reduced considerably. The relationship between visual acuity and luminance of the test field was determined in glare--sensitive patients using a relatively simple method and a large range of luminances (0.1-30,000 cd/m2). In contrast to previously used methods, visual acuity was determined in a range where neuronal mechanism can be expected to be responsible for adaptation to brightness. We found disturbances in the relationship between visual acuity and luminance in several diseases, and it was especially pronounced in cone dystrophies. Affections of the optic nerve and opacities of the optic media usually did not cause a marked decrease in visual acuity at high luminances. As a supplemental investigation to mesoptometry and nyctometry, the method described here primarily permits types of photophobia to be determined that are not caused by stray light. The dynamic nature of neuronal adaptation processes determined by this test has therefore considerable influence on visual acuity.

Adaptation, Ocular↗

[Use of a low dose prostaglandin F2 alpha in bitches].

The dosage of Prostaglandin F2 alpha used until the present (100, 250 and 1000 micrograms/kg bw), in order to treat pyometra in the bitch, was accompanied with side effects such as salivation, vomiting and diarrhea. In the present work, the efficiency of low dose Prostaglandin (20 micrograms/kg bw) was examined in two different groups of patients: Group 1: Included 9 bitches pregnant for a period of 5-7 weeks duration. Initially the bitches were treated 3 or 4 times per day with Prostaglandin F2 alpha. In these cases abortion took place within 4 to 11 days. Group 2: 12 dogs, suffering from pyometra, were treated 3 times per day with PGF2 alpha for 8 days. In 9 dogs the pyometra resolved and the bitches came in estrus 2-5 months after treatment. 7 bitches have been mated and 6 of these gave birth to healthy litters. During a follow-up period of at least 10 months there has not been a reoccurrence of pyometra. In 3 out of the 12 dogs the uteri were still enlarged after 8 days of treatment. These bitches underwent ovariohysterectomy and a cystic hyperplasia of the endometrium was diagnosed histologically. The low dose (20 micrograms/kg BW) Prostaglandin F2 alpha induced in all dogs the expulsion of the uterine contents. Side effects during the treatment were not observed.

Abortion, Induced↗

The evaluation of an intermediate care--geriatric evaluation unit in a Veterans Administration Hospital.

In response to the increasing care needs of geriatric patients and attendant hospital costs, the Nashville Veterans Administration Medical Center, which has 393 beds and admits 8400 patients annually, initiated an Intermediate Care Service in 1988. A geriatric team was formed, sharing staff and resources from existing units. To determine the efficacy of intermediate care, automated data sources at the Nashville Veterans Administration Medical Center provided data on discharge status, length of stay, and diagnoses of patients in both the acute and intermediate care units. The first year's experience indicated that careful communication and education of nursing staff was required to initiate the Intermediate Care Service with no staff resigning. An interdisciplinary team facilitated better patient care and discharge planning. Among 190 patients discharged from this service, 57% were discharged home and 22% into nursing homes; this can be compared to those discharged from acute care units of the hospital: 84% home and 4% to a nursing home; 20% of the patients in the Intermediate Care Service were discharged to a lower level of care than the initial hospital discharge plan had indicated. A 1.4-day decrease in average length of stay in the hospital has occurred since initiation of the Intermediate Care Service.

Aged↗

[Chronic eosinophilic keratitis in the cat].

A special form of keratitis in the cat is described on the basis of 8 clinical cases. The disease has been known in the United States and the United Kingdom for some time, however, it has, to our knowledge, never been described in Switzerland. This keratitis is characterized by chronicity and infiltration of the cornea by mast cells and eosinophils. It is usually an unilateral and painless condition. We describe the clinical features and diagnostic examinations of the disease. Cytology of a corneal scraping is usually diagnostic. As in the cases described in the literature the cats were successfully treated with oral megestrol acetate. The aetiology of the disease is unknown.

Animals↗

Disseminated skeletal lesions associated with pathogenic actinomycetes in a Pygmy hog (Sus salvanius).

The clinical and pathological features of an unusual crippling bone disease in an adult male Pygmy Hog, Sus salvanius, born the smallest in a litter of five and representing the rarest of the known living Suidae, are described. Radiological studies revealed severe spondylosis deformans and focal sharply demarcated radiolucencies in virtually the whole skeleton, but particularly in the bones of the skull, the processes of multiple vertebrae, the ribs, scapulae and parts of the humeri and femora. The clinical chemistry measurements were indicative of pathological lytic processes in the skeleton. The focal bone lesions consisted of caseous necrosis, dystrophic calcification and peripheral fibroblastic demarcation. They contained colonies of filamentous bacteria identified as members of the Order Actinomycetales. Case history evidence suggests that the infection may have resulted from repeated skin trauma inflicted by litter-mates.

Actinomycetales Infections↗

[Causes of death and disease in kittens].

Post-mortem examinations were carried out on 168 kittens 0 to 12 weeks of age. One third of the kittens died of an infectious agent, one third showed non infectious illnesses and in one third the examinations revealed none or vague results.

Animals↗

Treatment of urinary incontinence in dogs by endoscopic injection of Teflon.

Twenty-two dogs with urethral sphincter incompetence, nonresponsive to phenylpropanolamine administration, were treated by urethral submucosal injection of Teflon. Urinary continence was achieved in all dogs for at least 2 months. Urinary incontinence recurred in 14 dogs (64%) and was controlled by a second Teflon injection in 11 of 12 dogs (92%). Minor complications included transient stranguria, with or without hematuria, after 4 of 35 injection procedures. One dog had temporary partial urethral obstruction after treatment.

Animals↗

[Pathological findings in lentivirus infected cats].

This report describes the necropsy findings in 3 cats with a natural T-lymphotropic Lentivirus (FTLV) infection. The changes are compared with the "immunodeficiency syndrome" of humans and monkeys. Furthermore, the pathogenicity of the FTLV and the significance of a dual infection with FTLV and Spumavirus is discussed.

Animals↗

[Feline infectious peritonitis].

This paper gives a summary of our present-day knowledge concerning etiology, clinical aspects, diagnosis, pathology and pathogenesis of feline infectious peritonitis. Special emphasis is given to the participation of the immune system in the development of lesions. A therapy protocol is proposed and an extensive list of original literature for further study is given.

Animals↗