Biomedical subjects

B Heber

Publications and source records attributed to B Heber.

8 recordsLinked to original sources

PubMed1987

[Wind tunnel studies of inner city areas].

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Air Movements↗

PubMed1982

[On the different release kinetics of water-soluble and lipid-soluble forms of hydroxyquinoline in oleogel ointment bases (author's transl)].

Studies using the model according to Horsch and Kögel showed that the release kinetics of the suspended water-soluble (but not lipid-soluble) drugs hydroxyquinoline sulphate and hydroxy-quinoline sulphate--potassium sulphate from oleogels is of a zero order. Differences in drug dispersity do not affect the release rates. Oleogels containing the lipid-soluble hydroxyquinoline base yielded undersaturated solution ointments, the release kinetics of which can be stated by a semilogarithmic relationship. There exists a linear correlation between the release rates and the product of the lipid solubility of the drug and the reciprocal apparent distribution coefficient.

Chemistry, Pharmaceutical↗

PubMed1982

[Contributions to the liberation of drugs from suspension ointments. Part 19: Studies on the interactions of hydroxyquinoline (salts) with ointment components (author's transl)].

On studying the interactions of hydroxyquinoline and its watersoluble salts with substances commonly used to ointment preparation, the authors stated a large agreement between the decreases in release rate and the quotients of binding determined by equilibrium dialysis. Sodium carboxymethyl cellulose, zinc oxide, and talc react with these drugs to form bindings of some strength the impair the release of the drugs, whereas hydroxyethylcellulose and Aerosil behave indifferently.

Chemistry, Pharmaceutical↗

PubMed1981