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Biomedical subjects

B Heisig

Publications and source records attributed to B Heisig.

15 recordsLinked to original sources

Results of aortoventriculoplasty in 21 consecutive patients with left ventricular outflow tract obstruction.

Results of aortoventriculoplasty (AVP) are reported in 21 patients with various types of left ventricular outflow tract obstruction (LVOTO). The concept of AVP is based on creating a surgical aortoseptal defect which is patched to provide the largest possible outflow tract to the left ventricle. Lesions consisted of isolated diffuse fibromuscular subaortic stenosis in six patients, diffuse subaortic stenosis and associated other cardiovascular anomalies in five, hypoplastic aortic anulus in two, idiopathic hypertrophic subaortic stenosis (IHSS) in two, and stenosis of a previously implanted aortic valvular prosthesis in three patients. Ten patients had had at least one unsuccessful previous surgical attempt to relieve the LVOTO. The coexisting mitral incompetence in IHSS disappeared after AVP alone. Immediate postoperative hemodynamic results were excellent in all cases. Postoperative death in five patients was due to advance myocardial failure in two, brain damage in one, transection of a dominant septal artery in one, and severe acidosis with renal failure in the last case. However, in the last 16 patients (17 operations) the only death (5.8 percent) was that caused by uncontrollable acidosis. Follow-up results indicate that 16 patients are clinically doing well, and hemodynamic studies in 14 patients are rated as excellent or good from 1 to 25 months postoperatively. It is concluded that AVP is an effective operation for managing all types of LVOTO and can be used routinely with an acceptably low mortality rate.

Aorta

[The portacaval anastomosis (author's transl)].

All patients treated in the authors' clinic for portal hypertension from 1958 to 1975 are reviewed and the problems encountered with portacaval anastomoses are explained with special reference to encephalopathy and hepatic failure. Intrahepatic block was recorded in 88% of 722 patients. Portacaval anastomoses were constructed in 292 cases, splenorenal anastomoses in 175, and mesenterico-caval anastomoses in 12. Among the patients with stationary cirrhosis, the 6-year survival was unrelated to the type of operation performed and amounted to approximately 70%, while 6-year survival was only 40% in patients with progressive cirrhosis of the liver, whether they received surgical or conservative treatment.

Esophageal and Gastric Varices

[Glucose and lactate concentration in tears of rabbits following mechanical stress and wearing of contact lenses].

The concentration of glucose and lactat in tears is significantly different after slight or strong irritation of the eye. More glucose and lactat can be washed out of alterated tissue compared to normal one, although we estimate that the metabolits are primary more secreted after irritation. Under soft contact-lenses the concentration of both metabolits increase continiously during a certain period. Under hard contact-lenses the single measurements are very different. We have to estimate many disturbing factors.

Animals