Evaluation of thyrotropin-releasing hormone as a potential antidepressant agent in the conscious dog.
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Animals↗
Biomedical subjects
B Hine
Publications and source records attributed to B Hine.
Loss of catecholamine derivatives during gas-liquid chromatography.
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Catecholamines↗
EEG seizure anomalies following supramaximal intensities of cortical stimulation: relationships with passive-avoidance retention in rats.
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Amnesia↗
Increases in heart rate accompanying decreases in activity and defecation: support for a dual process theory of habituation.
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Animals↗
Retrograde amnesia: production of skseletal but not cardiac response gradient by electroconvulsive shock.
Rats given a single electroconvulsive shock immediately after but not 60 seconds after an aversive conditioning trial exhibited behavioral retention deficits 24 hours later in a one-trial passive avoidance task. In contrast to these differential performance deficits, similar heart-rate changes, indicative of fear retention, were seen in punished animals irrespective of the time of delivery of the shock. These data suggest retention of a generalized fear to the training experience that was not revealed by the behavioral measure. The potential usefulness of concomitant behavioral and physiological response assessment in consolidation research is discussed.
Amnesia↗