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Biomedical subjects

B Hwang

Publications and source records attributed to B Hwang.

At least 109 records · Page 6Linked to original sources
PubMed1991

Pneumothorax: a complication of deep endotracheal tube suction: report of 3 cases.

Endotracheal suction plays a major role in providing airway care but it is nor without inherent hazard. In routine practice of pediatric intensive care, the suction catheter is usually inserted until slight resistance is felt and is then withdrawn. Here we report three instance in last year of a rare complication of suction - secondary pneumothorax after bronchial perforation due to deep endotracheal suction. It should always be first suspected in an infant who suddenly deteriorates during or after such suction procedure. Premeasurement of the appropriate depth for catheter insertion, with the tip no more than 1 to 2 cm beyond the carina, is also suggested to minimize or prevent this complication.

Female↗
PubMed1991

New therapy for hydrocarbon pneumonitis--nasal prongs continuous positive airway pressure (NPCPAP).

Respiratory failure and conscious disturbance developed in a 18-month-old girl following ingestion of an unknown quantity of spot remover solution, a petroleum distillate product. Rapid deterioration was noted within 2 hours after ingestion. The patient became stable in condition and dramatically improved through intensive care with respiratory support by using nasal prongs continuous positive airway pressure (NPCPAP). To our knowledge, this may be the first case being successfully managed with this technique.

Female↗
PubMed1990

The prevalence of allergic disease and IgE antibodies to house dust mite in schoolchildren in Taiwan.

The prevalence of positive specific IgE antibodies to house dust mites (Dermatophagoides pteronyssinus; D. farinae) was determined by enzyme-linked immunosorbent assay (ELISA) in 5097 (61%) volunteers of 8345 schoolchildren aged between 7 and 14 yr from two government schools. All of them filled out a questionnaire concerning allergic symptoms. Among them, 412 (8.1%) children showed a positive reaction to at least one of the two mite allergens, the range varying between 5.6 and 11.2% according to the child's age. Boys had higher prevalence of positive mite specific IgE than girls (9.8% vs. 6.4%, P less than 0.01), with the overall male to female ratio 1.5:1. The prevalence of bronchial asthma in boys and girls was 5.3% and 3.3% respectively. The positive mite specific IgE antibody in children with asthma and allergic rhinitis was 52% (103 of 198) and 28.7% (193 of 673) respectively. The mean levels of mite specific IgE were not significantly related to the age of onset and severity of asthmatic symptoms (P greater than 0.1), but were significantly different among subjects with current and past asthma (P less than 0.001). It is suggested that the mite-specific IgE may play a role in the pathogenesis of bronchial asthma in children.

Adolescent↗
PubMed1989

A study of the effect of humidification on temperature of incubators in the nursery in Taiwan.

To test whether it is necessary to humidify incubators in Taiwan, over a one-year-period, 180 sets of simultaneous recordings including room temperature, room humidity, incubator temperature and incubator humidity were collected. Water was randomly added to half of the incubators. Cultures from those and swab cultures from the other half, or the dry humidifiers were presented simultaneously for examination. Results showed that incubator humidities were unaffected by seasonal changes, while room humidities did change with the seasons. Adding water to incubators could raise the humidity to a significantly higher level (mean +/- SD: 60.70 +/- 7.86%) than in those without water (mean +/- SD: 50.30 +/- 6.45% P less than 0.01). Bacterial growth rate of incubators with water was significantly higher (89.09%) than those without water (37.93%, p less than 0.01), but the organisms cultured could not be related to babids' illnesses on clinical and/or laboratory grounds.

Bacteria↗
PubMed1988

Detection of house dust mite allergens and immunoblot analysis in asthmatic children.

The mite allergen extracts (Dermatophagoides pteronyssinus and D. farinae), were fractionated by polyacrylamide gel electrophoresis and autoradiography. The molecular weight of the most apparent proteins of D. pteronyssinus was between 27,000 and 35,000, and the protein components of D. farinae were in the 9-100-kilodalton range. Specific IgE antibodies directed against mite allergens were utilized as probes to detect the allergens. Using immunoblot analysis and radiostained technique, D. pteronyssinus-sensitive patient sera displayed the major protein of allergens with molecular weights of 15,800 and 27,000-31,000, while D. farinae-sensitive patients' sera displayed the major protein of allergens with molecular weights of 12,000, 15,800 and 26,000-29,000. The electroblotting technique is fast, convenient, and highly suitable for both allergen composition studies and screening of antibody specificities.

Allergens↗
PubMed1987

Pompe's disease in Chinese and prenatal diagnosis by determination of alpha-glucosidase activity.

We measured the activities of two major forms of alpha-glucosidase in lymphocytes and cultured fibroblasts from normal healthy controls and patients with Pompe's disease by using 4-methylumbelliferyl-alpha-D-glucoside as substrate. We found (1) enzyme activity of the pH 4 and pH 6 forms varied with age, and (2) patients with Pompe's disease showed very low activity of the pH 4 form and a low ratio of pH 4 to pH 6 forms. We established a reference range and were also able to diagnose prenatally the homozygote and heterozygote forms of Pompe's disease which occurred in families of southern Chinese and aborigines in Taiwan. This enzyme biochemical study may be useful in anthropology.

Age Factors↗
PubMed1987

Systemic lupus erythematosus in children.

A retrospective study was made of 137 children with systemic lupus erythematosus (SLE) seen at the Veterans General Hospital in the past 12 years. There were 116 females (84.7%), and 21 males (15.3%). The peak ages of onset were 13-14 years and 16-17 years. Malar rash, arthritis and fever were the most common presentations, as in previous studies. Central nervous system (CNS) involvement occurred in 24 cases (17.5%), and renal disorder was noted in 77 cases (56.2%). Renal biopsy in 67 cases showed a pathological transformation rate of 16.1% (5/31). Ten patients died during the study period, with renal insufficiency the primary cause of death.

Adolescent↗