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Biomedical subjects

B I Davydov

Publications and source records attributed to B I Davydov.

At least 37 records · Page 2Linked to original sources
PubMedDate not supplied

[Effect of mexamine on the resistance of dogs to acute hypoxic hypoxia].

As demonstrated in experiments staged on dogs mexamine hydrochloride, used in a dose of 20 mg/kg by the intraperiotoneal route 1.5 hours before the onset of acute hypoxic hypoxia increases the resistance of the organism to oxigen deficiency. Mexamine is capable of significantly intensity hypothermy in dogs during acute hypoxic hypoxia.

5-Methoxytryptamine↗
PubMedDate not supplied

[Video display terminals: their electromagnetic safety].

Widespread application of video terminals (VT) has led to accumulating some unambiguous data on harmful effect of electromagnetic and electrical fields on the health. An analysis indicates that the level of electromagnetic and electrical fields is below permissible limits. IRPA/INIC concludes that the electromagnetic effects on VT users health are unharmful. However, the problem of VT use is an integrated one and involves not only radiation but ergonomic aspects and in this context requires further studies.

Computer Terminals↗
PubMedDate not supplied

[Pharmacologic defense of the brain in radiation injury: some arguments].

Based on an analysis of the latest data on the problem of pharmacologic defense, the pro and contra scientific arguments of using pharmacochemical countermeasures to radiation damages of the brain are discussed in succession. A comparative characteristic of positive and negative effects of countermeasures possessing various neurotropic properties is presented. A general scheme of searching for the means of pharmacologic correction of radiocerebral syndrome involving the following stages: pathophysiologic analysis of cerebral disorders; selection of behaviorally significant (psychophysiologic) criteria; search for pharmacochemical correction means; experimental animals studies with extrapolating their results to a man; radiocerebral syndrome simulation (pharmacologic, physical and chemical); field tests; decision-making (medico-biological and formalized approaches) is presented. "Pyramid of complexity" of radiocerebral effects extrapolation from the animals to a man to suit an hierarchy of the biological structures is presented. The effectiveness of conditionally-quantitative relationships of the drugs of prolonged and short-term effect as applied to various radiation syndromes (erythropoietic, gastrointestinal and cerebral) is discussed.

Aerospace Medicine↗
PubMedDate not supplied

[Socio-psychological and ecological aspects within the system of nuclear radiation risk mitigation].

The authors bring into light several aspects of nuclear radiation risks, i.e. physical safety of nuclear technologies and ecology, place of operator within the nuclear radiation safety system (proficiency, protective culture, safety guides) and consider approaches to the human factor quantification within the system of mitigation of risks from nuclear technologies, and IAEA recommendations on probable risk estimation. Future investigations should be aimed at extension of the radiation sensitivity threshold, personnel selection as by psychological so genetic testing for immunity to ionizing radiation, development of pharmachemical and physical protectors and methods of enhancing nonspecific resistance to extreme, including radiation, environments, and building of radiation event simulators for training.

Ecology↗
PubMedDate not supplied

[The effect of adrenaline on the succinate dehydrogenase activity in functionally changed (lymphoid leukosis) lymphocytes in mice].

The activity of succinate dehydrogenase (SDH) in lymphocytes of peripheral blood of AKR mice was measured in response to intraperitoneal injection of epinephrine hydrochloride at a dose of 1 mg/kg. SDH reactions to epinephrine were of two types: increase or decrease of activity. The type of reaction depended on the initial enzyme level. The decrease of epinephrine activation of SDH in lymphocytes was found to be correlated with the age of animals and hematological manifestations of hemoblastosis they developed. The percentage of cells with a high SDH activity in hemoblastotic animals was correlated with the count of prolymphocytes and blast cells in peripheral blood.

Animals↗
PubMedDate not supplied

[The effective dosage as the stimulating exposure in fractionated gamma irradiation].

The study of early neurological disturbances (END) in rats after fractionated gamma irradiation with doses of 37.5-225 Gy at dose rate of 30.11 Gy/min has demonstrated that the initial response of animals to pulse ionizing radiation is a function of the electric charge induced by ionizing radiation. A change in the probability of occurrence of each of the END symptoms, with the increased intervals between exposures, is merely an indirect indication of the eliminating mechanisms and is intricately connected with the irritating charge value. The period of dose half-elimination in 16 min. The threshold effective dose rate leading to END is of the order of 2.12 Gy/min. The proposed empiric relationships permit to correlate the probability of END symptom occurrence with the continuous quantitative parameter of fractionated irradiation, that is, with an effective dose as an analogue of the irritating effect.

Animals↗
PubMedDate not supplied

[Effect of urea and pituitrin on cerebral radiation effects in rats].

The administration of urea and pituitrin produced a directed and rapid change in a hydration profile of brain tissue which permitted to modify the severity of cerebral radiation affection in rats, that is, to increase it with hypohydration and to decrease with hyperhydration of the brain.

Animals↗
PubMedDate not supplied

[Epidemiologic studies of the effect of microwaves (neurophysiologic, hematologic and ophthalmologic aspects)].

This paper presents epidemiological and clinical evaluations of subjects exposed to electromagnetic radiations (EMR) in the microwave range with emphasis on neurophysiological, hematological and ophthalmological changes. Special attention is given to neurological and psychogenic effects of EMR as well as to possible development of radiophobia. Ageing, cataract development and genetic signs are considered as objective measures of EMR effects.

Action Potentials↗
PubMedDate not supplied

[Structuro-functional organization of the blood-brain barrier].

The analysis of the authors and published data allowed to conclude that the blood-brain barrier was a complex structural-functional system. Its basic components are endothelial cells, basal membrane, pericytes, tissue basophils, and astrocytes. The role of these structural elements in the permeability of blood-brain barrier has been studied. Organ-specific peculiarities of the brain tissue basophils have been established in rats, cats, and dogs. The astrocyte-capillary complexes were found to be very reactive, and at the same time, very plastic CNS structures.

Animals↗