NRC, NCRP, ICRP and recommendations on prenatal radiation exposure.
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Biomedical subjects
Publications and source records attributed to B I Martins.
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An analysis of the theories and experimental data dealing with dose-rate effect, relative biological effectiveness (rbe), and oxygen enhancement ratio (oer) for mammalian cells, indicate that neither the theories nor the experimental data themselves are helpful in establishing general rules regarding variations of rbe or oer with dose-rate. There are inconsistencies among the theories which are often at variance with experimental data, which too, are inconsistent among themselves.
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The colony-forming ability of cultured mammalian cells exposed to monochromatic ultrasonic vibrations of different frequencies (0.1, 0.5, 1.0, 2.0, 3.3 MHz) was studied. The combined effect of x rays and 1.0-MHz ultrasonic waves on the survival of M3-1 cells was also investigated. Split-dose experiments showed that cells exposed to ultrasound are "sensitized" to a subsequent exposure. Almost twice as many cells survive a given ultrasonic dose when exposed in the M phase as when exposed in the S phase. A small amount of synergism between ultrasound and x rays has been observed. The extent of synergism depends on the experimental factors, and may be due to an interaction between nuclear damage caused by x rays and the damage to the cell membrane caused by ultrasound.
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