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Biomedical subjects

B I Shulutko

Publications and source records attributed to B I Shulutko.

67 records · Page 4Linked to original sources
PubMed1977

[Morphology of cirrhosis of the liver in hepato-cerebral dystrophy (according to needle biopsy findings)].

The paper presents data of a luminous microscopy of the liver that were obtained by aspiration biopsy in 23 patients with hepato-cerebral dystrophy in comparison with 25 patients with cirrhosis of a hereditary etiology. In the majority of the cases (21 from 23) the method of puncture biopsy of the liver provides the diagnosis of cirrhosis in hepatocerebral dystrophy. The complex use of histochemical methods and especially staining for reticuline and cuprum significantly increases its informativeness. In 15 of 28 patients cirrhosis was of a mixed character (postnecrotic and portal), in 5 patients--postnecrotic and in a preneurologic stage it corresponded to the initial features of portal cirrhosis. The damage of the liver precedes the brain damage and is connected with an excessive accumulation of cuprum in it, the amount of which is significantly higher (559 +/- 89 mkg/g of dry weight) in the patients with hepato-cerebral dystrophy in comparison with the patients with cirrhosis of some other etiology (111.0 +/- 19.0 mkg/g of a dry weight).

Copper↗
PubMed1976

[Functional and morphological state of the liver in secondary cholangitis].

Studies on the liver state from the functional-morphological point of view in patients with acute and chronic secondary cholangitis have revealed in all cases the involvement of hepatic parenchyma with the development of cholangiohepatitis. In its acute course and timely performed operative interventions the process in the liver tends to subside. The authors consider that due to the absence of pure forms of cholangitis this term seems to be questionable, and they recommend to substitute it in all cases by the term cholangiohepatitis.

Biopsy, Needle↗
PubMedDate not supplied

[Effect of protectors on morphofunctional changes in rat kidneys in tourniquet shock].

The protective effect produced on the kidneys in tourniquet shock by thiol agents possessing antioxidant properties (unithiol, cystamine) was compared with that of a preparation of cell capsules of L. bulgaricus (CCLB). Tourniquet shock was modeled under ether Raush anesthesia by applying 8 turns of a rubber tourniquet to the hind limbs for 6 hours. Thirty minutes before removal of the tourniquet animals of the first group were given an injection of 1 ml of physiological solution, animals of the second group--20 mg/kg of unithol, those of the third group received an injection of 20 mg/kg of cystamine hydrochloride. Animals of the fourth group received 50 mg/kg of CCLB in 1 ml of physiological solution 7 days before the experiment. A marked protective effect of CCLB on the kidneys in tourniquet shock was established. According to the degree of the protective effect on the tissue of kidneys in tourniquet shock, the studied agents come in the following order: CCLB, cystamine, unithiol.

Animals↗
PubMedDate not supplied

[Disorders of oxidation-reduction processes in nephrotic syndrome].

Reduction capacity of the blood and its fractions was studied by potentiometry in 68 patients with the nephrotic syndrome. The type of renal injury was identified by kidney biopsy in all the patients. Control group consisted of 30 donors. Changes of blood reduction capacity were detected in all the patients with the nephrotic syndrome in comparison with the controls. A correlation could be traced between blood reduction capacity and functional compensation of the nephrotic syndrome. Disordered redox equilibrium was not associated in patients with the nephrotic syndrome with increased levels of lipid peroxidation products. The method used to assess reduction capacity is highly informative, rapid, and simple.

Blood Volume↗