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Biomedical subjects

B I Wenzel-Hora

Publications and source records attributed to B I Wenzel-Hora.

27 records · Page 2Linked to original sources
PubMed1983

Differential diagnosis of lymphedema after indirect lymphography with Iotasul.

Indirect lymphography with Iotasul (interdigital, intradermal infusion) was performed in 32 patients with lymphedema. No side effects were observed. Opacification of the peripheral lymph vessels reveals two distinct patterns: 1. No, few, or only very small-calibre lymph vessels ("hypoplasia"): 17 patients (primary lymphedema in 14 cases, secondary in 3). 2. Many large-calibre (dilated) lymph vessels ("hyperplasia"): 15 patients (primary lymphedema in 2 cases, secondary in 13). An occasional finding in "hypoplasia" is drainage of the contrast material in the region of the adventitia of vessels, and a network of extremely fine lymph vessels apparently corresponding to the dermal plexus is sometimes observed. Because it leads to the opacification of barely perceptible lymph vessels in the extreme periphery which were previously inaccessible to radiology, indirect lymphography offers a genuine gain in information and improves the differential diagnosis. When administered correctly, Iotasul invariably enhances the peripheral lymph vessels without making any great demands of the patient or investigator.

Adolescent↗
PubMed1982

[Indirect lymphography at the eye and in the face- and neck-region with iotasul (author's transl)].

For the first time the lymphatic pathways of the conjunctiva and the eyelids of dogs could be presented in vivo with the water-soluble X-ray contrast medium iotasul. By means of indirect application the lymph flow could be demonstrated up to the truncus jugularis. Because of the simultaneous infusion of the contrast medium at different points the lymphography of the face- and neck-region is considerably facilitated.

Animals↗
PubMed1981

Iotasul, a water-soluble (non-oily) contrast medium for direct and indirect lymphography: radiological and morphological investigations in dogs.

Radiological, light microscopic and electron microscopic findings after direct and indirect lymphography with Iotasul, a new non-ionic water-soluble (not oily) contrast medium, are reported. The results of the studies in 18 dogs clearly show that the roentgenological demonstration of the lymph system following intralymphatic administration of Iotasul in the dog is not inferior to that following the use of conventional oily con contrast medium passes quickly to the lymphatic system and the lymph nodes and is eliminated within 24 hours. The complications and tissue reactions known from oily contrast media are not observed following use of the new water-soluble contrast medium. Furthermore, studies of the fine structures show unequivocally that no morphologically detectable changes attributable to the contrast medium occur either in the region of the injection or in the lymph vessels, lymph nodes and organs such as kidney, liver, lung, spleen and myocardium. Preliminary studies indicate that the new contrast medium offers the possibility of indirect demonstration of lymph vessel regions and groups of lymph nodes (indirect lymphography) which have largely escaped detection by the previous routine lymphographic examination.

Animals↗
PubMed1980

Iotasul, a water-soluble contrast agent for direct and indirect lymphography. Results of preclinical investigations.

Iotasul, a non-ionic dimeric water-soluble contrast agent with outstanding physico-chemical properties is well suited for direct as well as indirect lymphography, as demonstrated in experimental animals. The contrast medium is eliminated practically completely within 24 hours by the renal route. The tolerance of this agent is far better than that of oily contrast media.

Animals↗