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Biomedical subjects

B J Blinder

Publications and source records attributed to B J Blinder.

15 recordsLinked to original sources
PubMed1993

A psychological "sense-of-control" profile of patients with anorexia nervosa and bulimia nervosa.

To investigate control and self-control issues for patients with eating disorders, 10 individuals diagnosed with anorexia nervosa or bulimia nervosa were compared to two sex-matched groups of 9 and 50 adults on the Shapiro Control Inventory. Analysis of variance and subsequent planned comparisons showed significant differences indicative of pathology between the eating-disordered group and one or both comparison groups on the general domain sense of control scale and the positive sense of control scale. Three of the four mode scales and the domain-specific sense of control scale were also in the expected direction. Several clinically relevant individual items also supported this trend. The discussion notes the clinical importance of refining how control is measured for eating-disordered populations.

Adolescent↗
PubMed1990

Comparison of regional brain metabolism in bulimia nervosa and affective disorder assessed with positron emission tomography.

Women with bulimia often present with symptoms of depression in addition to bingeing and purging behavior. Brain metabolism in eight women with bulimia nervosa was compared to that in eight women with major affective disorder and eight normal women, using positron emission tomography and 18-fluoro-2-deoxyglucose. Normal women have higher right than left cortical metabolic rates and active basal ganglia. Bulimics lost the normal right activation in some areas, but maintained basal ganglia activity. Depressives retained right hemisphere activation, but had decreased metabolism in basal ganglia. This suggests that although women with bulimia frequently present with symptoms of depression, the pathophysiologic changes associated with bulimia differ from major effective disorder.

Adult↗
PubMed1987

Two diagnostic correlates of dexamethasone nonsuppression in normal weight bulimia.

Evaluations of neuroendocrine abnormalities and possible relationship to major affective disorder in normal weight bulimic women have utilized the Dexamethasone Suppression Test (DST). In our sample of 29 bulimic women, 59% showed DST nonsuppression (DSTNS). Two diagnostic correlates were significant in relation to DSTNS: prior history of anorexia nervosa and current clinical DSM III diagnosis of depression. Eating Attitudes Test (EAT) scores were also significantly higher in the DSTNS group. The findings suggest that more extensive psychiatric disorder and ingestive abnormalities may be present in this subgroup of normal weight bulimic women who exhibit DST nonsuppression.

Adolescent↗
PubMed1986

Serum salivary isoamylase levels in patients with anorexia nervosa, bulimia or bulimia nervosa.

Salivary isoamylase levels were studied in a sample of 35 women with bulimia, anorexia nervosa, or bulimia nervosa. Salivary isoamylase elevation was related to the presence of sham eating, evidenced by elevated isoamylase values in patients with bulimia nervosa or bulimia, and depressed isoamylase values in patients with anorexia nervosa. Salivary isoamylase levels may provide insight and have bearing on the functional interrelationship between appetite regulation and ingestive behavior in patients with eating disorders, as abnormalities may occur during both the cephalic as well as the oral phase of eating.

Adolescent↗
PubMed1978

The children's psychiatric hospital unit in the community: I. Concept and development.

The authors describe a children's mental health unit (CMHU) in a general hospital and cite the need for short- and intermediate-term children's psychiatric facilities within the community. They point out the special need for psychiatric inpatient units for the 3-13 age group and note that in their CMHU the average length of stay and patient turnover ratio compare favorably with adolescent units, which they attribute to the emphasis on diagnosis and treatment rather than long-term rehabilitation.

Adolescent↗