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Biomedical subjects

B J Grossman

Publications and source records attributed to B J Grossman.

11 recordsLinked to original sources
PubMed1977

Mycobacterium kansasii arthritis of the knee joint.

Mycobacterium kansasii infection of the knee joint was diagnosed in an 11-year-old boy on the basis of skin testing to atypical mycobacteria, and a positive culture from a synovial tissur biopsy. Appropriate antituberculose drugs shoud be institute as sole treatment if no bony destruction is present. Ifthere is no response to chemtherapy, synovectomy should be performed.

Arthritis, Infectious↗
PubMed1977

Lupus-associated chorea in childhood.

Chorea associated with systemic lupus erythematosus (SLE) has been reported in only 28 patients. The clinical and laboratory features of these cases are reviewed here, along with those of a 7-year-old boy who, we believe, represents the youngest child reported to date. In approximately half of these 29 individuals, most of whom were children, chorea preceded other manifestations of SLE. The age range and clinical characteristics of lupus-associated chorea were not appreciably different from those of Sydenham's chorea and most of the patients in whom chorea developed before other manifestations of SLE were initially assumed to have Sydenham's chorea. Systemic lupus erythematosus should especially be considered if chorea begins in the older child or is associated with a persistently elevated erythrocyte sedimentation rate.

Child↗
PubMed1975

Chronic polymicrobial bacteremia.

A 13-year-old girl had chronic polymicrobial bacteremia with Enterobacter hafnia and Enterobacter agglomerans in the absence of any demonstrable underlying illness, use of immunosuppressive drugs, or discovery of portal of entry of the bacteria. She was treated successfully with a prolonged course of carbenicillin and aminoglycoside antibiotics which were tolerated well. The only side effect of the therapy was a transient episode of vestibular dysfunction which was reversible following cessation of gentamicin. The principles of management of polymicrobial bacteremia are presented.

Adolescent↗
PubMedDate not supplied

Screening blood donors for gastrointestinal illness: a strategy to eliminate carriers of Yersinia enterocolitica.

Recent reports of fatal transfusion-associated Yersinia enterocolitica sepsis prompted a study of the feasibility of adding a question to the routine donor health history as a method of reducing this risk. In three American Red Cross blood centers, 11,323 donors were asked one of two questions about gastrointestinal symptoms during their health history screenings. Affirmative responses were obtained from 0.6 or 4.0 percent of the donors, depending on how the question was asked. In one center, more than 6 percent of donors gave affirmative answers. The efficacy of asking a relatively simple question about gastrointestinal symptoms as a way of preventing Y. enterocolitica should be evaluated further, because relatively large numbers of donors may respond affirmatively. Other methods of reducing the risk of transfusion-associated Y. enterocolitica infection should be pursued.

Blood Donors↗