Biomedical subjects

B J Horn

Publications and source records attributed to B J Horn.

14 recordsLinked to original sources

PubMed2001

Nonuniform accumulation of cadmium and copper in kidneys of wild brown trout (Salmo trutta) populations.

Cadmium and copper accumulated nonuniformly in the kidney of wild brown trout on a longitudinal gradient as follows: the concentration in head kidney < anterior portion of tail kidney < posterior portion(s) of tail kidney. Zinc accumulated uniformly along the length of the kidney. Cadmium and copper accumulation in brown trout kidneys was lowest in the head kidney, where hematopoietic tissue dominates, and greatest in posterior tail sections, where filtration tissues dominate. Sampling programs designed to monitor cadmium and copper accumulation in trout kidneys should utilize the entire kidney, including the head kidney, to create comparable data sets.

Animals↗

PubMed1998

The effect of circuit compliance on delivered ventilation with use of an adult circle system for time cycled volume controlled ventilation using an infant lung model.

This in vitro study examined the effect of circuit compliance on delivered ventilation (VE) using a time-cycled, volume controlled circle system in an infant lung model. A Bio-Tek ventilator tester set to simulate normal and abnormal lung compliance measured VE delivered by the Narkomed 2B system. Circle circuits of varied compliance (2.75, 1.22 and 0.73 microliters.cm H2O-1) were tested. Tidal volume was adjusted to peak inflation pressures (PIP) of 20, 30, 40, and 50 cm H2O with three circuits, two lung compliances, and four different size tracheal tubes (TT) (2.5, 3.5, 4, 4.5 mm ID). Data were analysed using the multiple regression technique. Delivered VE was directly related to PIP and lung compliance. Delivered VE was not affected by the choice of circuit. TT size had minimal effects on VE when lung compliance was low; TT size was a more important factor when test lung compliance was normal. Extrapolating this data to the clinical setting, adequate ventilation of infants can be achieved with an adult circle system if an appropriate PIP is chosen, regardless of the compliance of the circuit used. Infants with poor lung compliance may require very high PIP for adequate ventilation.

Adult↗

PubMed1998

A comparison of three modes of ventilation with the use of an adult circle system in an infant lung model.

UNLABELLED: We examined the efficiency of an adult circle system with adult bellows to deliver minute ventilation (VE) to an infant test lung model. A Narkomed 2B system (North American Drager, Telford, PA) using three modes of ventilator setup were used: A = time-cycled, volume-controlled using bellows excursion to control delivered volume; B = time-cycled, pressure-controlled using inspiratory pressure limit adjustment to control delivered volume; C = time-cycled, pressure-controlled using the inspiratory flow adjustment to control delivered volume. VE was measured with two compliances (normal and low) and four endotracheal tube (ETT) sizes (2.5-, 3.0-, 3.5-, and 4.0-mm inner diameter). VE was measured at peak inspiratory pressures (PIP) of 20, 30, 40 or 50 cm H2O while respiratory rate (RR) was held constant at 20 breaths/min. VE was measured as RR was set at 20, 30, 40, or 50 breaths/min while target PIP was held constant at 20 cm H2O. Data were analyzed using the multiple regression technique. With the low compliance model, VE was nearly identical regardless of the ventilator setup. With the normal compliance model, minor differences in VE were observed, especially at the highest RR and PIP. VE was dependent on RR, PIP, and lung compliance. Overall, the ventilator setup resulted in minor changes in VE. Very high PIPs were required to deliver VE to the low compliance model. ETT size did not affect VE when lung compliance was low; however, smaller ETT size was a factor when test lung compliance was normal, decreasing delivered VE at higher PIP and RR. We conclude that with a Narkomed 2B adult circle system VE is dependent on PIP, RR, and lung compliance, but not on mode of ventilator setup. IMPLICATIONS: The results of this laboratory investigation indicate that when an adult circle system is used during infant anesthesia, the ventilation delivered depends primarily on the respiratory rate, peak inspiratory pressure, and the compliance of the lung being ventilated, rather than on the specific mode of ventilator setup.

Adult↗

PubMed1989

The mutual-participation relationship: key to facilitating self-care practices in clients and families.

The relationship among formal providers, clients, and families in home care is critical. If clients and family care givers are to develop adequate and safe self-care practices, they must be involved in mutual decision making concerning issues related to the illness and the care to be given. A relationship of mutual participation involves facilitating and negotiating goals with clients and their family members.

Family↗

PubMed1987