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Biomedical subjects

B J Klose

Publications and source records attributed to B J Klose.

At least 19 recordsLinked to original sources
PubMed1988

Mineral- and trace element concentrations in human breast milk, placenta, maternal blood, and the blood of the newborn.

The concentrations of the essential trace elements Cu, Fe, and Zn, and of the mineral elements Ca, K, Mg, and P during the perinatal period in human placenta and in the blood of the mother and the newborn (cord blood) were determined. Breast milk (colostrum and transitory milk) was also included to permit correlations between the different compartments. No correlations were found. The uptake by nutrition and the body-pools of the mother and their mobilization for these elements seem to be sufficiently high for an adequate supply of the fetus and the milk in the geographical region of Munich (Bavaria, FRG) under these investigations. Differences in the mineral-and trace element concentrations of colostrum and transitory milk for the elements P and Zn and to a lesser extent for Ca and Mg were observed. Additionally, breast milk samples from different geographical regions in Bavaria were investigated. Results for the heavy metals Cd, Hg, and Pb, and for the essential trace element Se are also presented for these samples, and can be seen as a reflection of the overall environmental and dietary influences during pregnancy in these geographical regions. ICP (Inductively Coupled Plasma)-emission spectrometry was used for the determination of the elements Cu, Fe, Zn, Ca, K, Mg, and P. For the additionally given elements in the milk-samples anodic stripping voltammetry (DPASV) (Cd, Pb), hydride atomic absorption spectrometry (AAS) (Se), and cold vapor AAS (Hg) were applied.

Female↗
PubMed1980

[Determination of aluminium in blood-serum by inductively coupled plasma (ICP)-spectroscopy (author's transl)].

The application of ICP emission spectroscopy for the direct determination of aluminium in blood serum was investigated and the method with all important parameters is described. The well known matrix interferences in atomic absorption spectroscopy do not exist in ICP spectroscopy, due to the very high excitation temperature of the sample of about 8000 K. It is therefore possible to perform very sensitive and reproducible measurements.

Aluminum↗
PubMed1976

[The influence of pregnancy on the venous return from the lower extremities (author's transl)].

Determination of intravenous pressure in the lower extremities revealed in 77 pregnant women a marked insufficiency of the venous drainage. In the last third of pregnancy the capacity of the venous drainage is reduced by approximately 30 per cent. Determination two to five days post partum showed a significant improvement but not yet complete normalization. The causes of the insufficiency of the venous drainage are hormonal influences, dilating the vessels, which are still active post partum. The insufficient venous return is a major factor in the genesis of varicosity during pregnancy. The disturbance of venous return by the large uterus will result in an increase of static venous pressure on the average of 10 mm Hg. In the upright position this is a qualitatively as well as quantitatively individually variable phenomenon. There ist no relation between the increase in static venous pressure and the occurrence of varicosity.

Adult↗
PubMed1976

[Breech presentation and its significance (author's transl)].

From 1959 to 1975, 1060 (3.6%) breech presentations were found among 29,463 infants. The breech deliveries from May 1, 1959 to December 31, 1965 were compared with those from January 1, 1966 to December 31, 1975. Among the 3.6% breech deliveries there were 47% male and 53% female. There were more primigravida breech deliveries in both groups. The mean age of the mothers was 25.4 years for primigravidas and 29.4 years for multiparas. There was a maternal mortality of 0.2% (2 cases) in breech delivery. 29% of the breech deliveries were premature deliveries. There was a strickingly high incidence of frank and full breech deliveries among all patients. Knee presentations were rare. Delivery was primarily accomplished with the Bracht manoeuver in over 80% of the cases. Complete breech extractions decreased and the incidence of Caesarean Sections rose from 6% in the first group to 21% in the second group of patients. During the past 3 years the Caesarean Section rate was approximately 30%. Perinatal complications in the breech deliveries compare well to those reported in the literature. Of 750 mature infants (70.8%), 12 died (1.6%). Discounting children with congenital malformations and intrauterine stillbirth there remained 5 deaths from breech deliveries (0.7%). Of 1032 breech deliveries with a birth weight of 1000 grams or over, 74 infants (over all perinatal mortality 7.2%) died. 110 infants of all breech deliveries had a birth weight of less than 2500 grams (prematurity rate 29.2%). Of 102 cases of perinatal mortality in breech deliveries including those below 1000 grams 90 (88.2%) were premature. Of those 90 premature deaths, 28 infants were less than 1000 grams. 25 infants showed fetal congenital abnormalities. The corrected perinatal mortality of the premature deliveries was therefore 11.9%. The rate of birth trauma was 6.3% in the first group and 2.7% in the second group.

Adult↗
PubMed1975

[Trace elements in the human placenta (author's transl)].

The determination of the mentioned elements was carried out by the neutron activation analysis with lollowing radio-chemical separation. The comparison of trace elements in the human placenta from different regions of Bavaria showed a high concentration of Sb, Br, La and Co in Munich. This fact is explained by the environmental pollution of the large city. Placentas from the Bavarian forest contained a higher amount of Ce and Hg. Cer is contained in the rock of this region. The increase in Hg from that region is unexplained.

Antimony↗