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B J Rosenbaum

Publications and source records attributed to B J Rosenbaum.

16 recordsLinked to original sources

Teicoplanin nephrotoxicity: first case report.

A 71-year-old man with type I diabetes mellitus was admitted to the hospital for the treatment of osteomyelitis of the left great toe secondary to methicillin-resistant Staphylococcus aureus. The patient was enrolled in an investigational protocol and was treated with teicoplanin 1200 mg/day. Following 40 days of treatment, the patient developed both markedly elevated serum creatinine and blood urea nitrogen. Urine analysis also showed the presence of protein. The eosinophils were markedly elevated in the blood. The patient was subsequently diagnosed with a probable drug-induced acute interstitial nephritis. Treatment with furosemide and hemodialysis over the next two weeks failed to produce improvement in renal function. The patient was referred for long-term dialysis. The data presented in this report suggest the possible relationship of teicoplanin and the development of renal failure in this patient. Periodic monitoring of renal function and follow-up are probably warranted in patients receiving long-term teicoplanin therapy.

Aged

The basilic vein fistula for vascular access.

The basilic vein fistula provides reliable vascular access for chronic hemodialysis therapy. Early morbidity includes edema and mild pain. Ischemic complications have not developed in this series. Patency has been excellent in the initial period and no patient has yet developed infection, aneurysm or venous fibrosis, although longer follow-up is necessary. The use of the autogenous basilic vein fistula in patients unsuited for forearm arteriovenous fistulae is supported by these results. Long-term results which would support continued use of this modality would include an expected lower incidence of infection due to the absence of a foreign body and the inherent healing property of viable tissue, and improved long-term patency attributable to the absence of a venous anastomosis.

Adult

Aeromonas hydrophila sepsis in a patient undergoing hemodialysis therapy.

Aeromonas hydrophila septicemia complicated by a generalized cutaneous vasculitis developed in a patient receiving home hemodialysis therapy. Because the Aeromonas organism is found in many natural water sources, the possibility that this patient's hemodialysis system became contaminated was explored. Although cultures from the patient's home environment showed no Aeromonas sp, the possibility still exists that the site of contamination was in the dialysis system.

Aeromonas

Dialysis acidosis.

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Acid-Base Equilibrium