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B J Wisniewski

Publications and source records attributed to B J Wisniewski.

4 recordsLinked to original sources

Factors affecting the incidence of infectious morbidity after radical hysterectomy.

A double-blind, placebo-controlled trial was performed to assess the value of cefoxitin for prophylaxis against postoperative infection following radical hysterectomy. Infectious morbidity was observed in 35% of 43 patients in the control group and 23% of 31 in the cefoxitin group. In seven control patients (16%) and one patient (3%) in the cefoxitin group the infections were related to the surgical site (p = 0.07). These differences did not achieve statistical significance. Examination of the data revealed a number of other factors, including operating time, patient weight, blood loss, and blood replacement, that were significantly related to the incidence of infectious morbidity. Comparison of the results of the present study with those in the literature indicates that a careful examination of the circumstances prevailing in any particular institution is necessary before a decision is made on strategies to combat infectious morbidity after radical hysterectomy.

Adult

Droperidol as an antiemetic in cis-platinum-induced nausea and vomiting.

23 patients received cis-platinum, doxorubicin and cyclophosphamide for gynecologic malignancy between December 1, 1980 and December 1, 1982. Each patient was randomized with each course of chemotherapy to receive intravenous droperidol or the combination of promethazine and chlorpromazine rectal suppositories as an antiemetic regimen. Both the rate and duration of emesis were significantly lower when droperidol was used as the antiemetic regimen. There were no major side effects with either regimen. Droperidol seems to be superior to the combination of promethazine and chlorpromazine rectal suppositories in alleviating cis-platinum-induced nausea and vomiting.

Adult

Abdominal wound closure using a nonabsorbable single-layer technique.

A continuous 1-layer abdominal closure using number 2 polypropylene was employed in 200 unselected consecutive patients. All the patients had lower midline incisions and were high-risk, and the majority (82%) had some form of gynecologic malignancy. A significant number had received preoperative radiotherapy (22.5%), another 18% were obese (over 90 kg), and 15% had undergone bowel surgery. The complete evisceration rate in the series was 0. A total of 17 (8.5%) wound infections occurred and 10 (5%) postoperative ventral hernias were seen over a 2-year period. Five of these were incisional and 5 were paraincisional; 1 of each required surgical repair. The method is simple, time-saving, and successful; it carries a low complication rate for patients at high risk for postoperative evisceration.

Abdomen