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Biomedical subjects

B Jaques

Publications and source records attributed to B Jaques.

27 records · Page 2Linked to original sources

Indications for combined orthodontic and surgical (orthognathic) treatments of dentofacial deformities in cleft lip and palate patients and their impact on velopharyngeal function.

Malformations, deformations and abnormal intermaxillary relationships varying in severity can be found in cleft lip and/or palate children. Such multiple deformities have an influence on speech resonance and articulation, as well as on masticatory, auditive and respiratory functions. Therefore, a multidisciplinary team should monitor these patients from birth on to adulthood. This article describes our treatment protocol, discusses the limitations of dental orthopedic action and the indications for orthognathic surgery. Timing and techniques of different surgical interventions are presented and the impact of these procedures on velopharyngeal function is evaluated.

Cephalometry↗

Unusual complications at iliac crest bone graft donor site: experience with two cases.

OBJECTIVE AND IMPORTANCE: Two cases of fracture of the iliac crest after graft harvesting are presented. Only six such cases have been reported in the literature, although more than 100,000 such procedures are performed each year in the United States alone. This complication adds to the morbidity of the procedure for which the graft is taken. Its avoidance by an appropriate harvesting technique will reduce patient disability and shorten hospital stay. CLINICAL PRESENTATION: A 56-year-old man who worked as a mechanic underwent anterior cervical discectomies and fusion at C5-C6 and C6-C7 for spondylotic radiculopathies. Another patient, a 48-year-old man, required mandibular reconstruction for squamous cell carcinoma. Both grafts were harvested from the iliac crest using osteotomies. On the 9th and 3rd postoperative days, respectively, each patient developed groin pain while walking, associated with marked tenderness over the graft donor sites. X-rays showed fractured iliac crests. INTERVENTION: Apart from bed rest for pain, no specific treatment was required. CONCLUSION: The use of the osteotome weakens the iliac crest, leading to stress fractures caused by the pulling action of the attached muscles. To prevent this from happening, we recommend the use of the oscillating saw, leaving a 3-cm spike of iliac crest anteriorly. Nevertheless, this complication has a good long-term outcome.

Bone Transplantation↗

[Indications and complications of free micro-flaps in ORL oncology].

Eighty-three free flaps were used to repair head and neck cancer defects between 1993 and 1995. The flaps used were 37 (44%) radial forearm flaps, 29 (35%) iliac crest flaps, 8 (10%) free jejunum flaps, 4 (5%) fibula flaps, 3 (3%) latissimus dorsi flaps and 2 (2%) rectus abdomini flaps. The indications for each flap are discussed. The flap loss rate was 4.8%, which led to reoperation with a new free flap in 3.6% of the cases. The other complications are discussed. Pre and post operative radiotherapy had no influence on the outcome of the free flaps. The mean duration of hospitalisation was 36 days. 78% of the patients who underwent a mandibular reconstruction were fitted with a fixed dental prosthesis and had normal mastication. 66% of the patients with oropharyngeal reconstruction had normal deglutition and 30% had a mixed diet. The acceptable complication rate, the good esthetic and functional results obtained with free flaps indicate that they should be used as a first choice technique in the reconstruction of head and neck cancer defects.

Adenocarcinoma↗

Factors predicting duration of delayed graft function in non-heart-beating donor kidney transplantation.

Non-heart-beating donors (NHBDs) are an important potential source of donor organs, but kidneys from such donors are prone to delayed graft function (DGF) and primary nonfunction, which are multifactorial in origin but believed to be mainly due to warm ischemic injury. This retrospective study examined a series of 88 transplants from Maastricht category II and III NHBDs to examine the role of factors to predict the duration of DGF. The main factors affecting duration of DGF were total warm ischemic time, cold ischemic time, product of perfusate GST concentration and donor age, quality of postoperative graft perfusion, incidence of acute rejection, recipient cardiovascular risk score, maximum pressure on machine perfusion, and weight gain during machine perfusion. Primary nonfunction was not accurately predicted from these factors for kidneys that had passed the viability assessment.

Age Factors↗