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B Jovanović

Publications and source records attributed to B Jovanović.

At least 19 recordsLinked to original sources
PubMed1996

Enteroaggregative Escherichia coli associated with an outbreak of diarrhoea in a neonatal nursery ward.

Over a 9-day period in February 1995, 16 newborn babies (age range 2-11 days) and 3 infants (24, 47 and 180 days of age) in a neonatal nursery ward developed diarrhoea accompanied by pyrexia and weight loss. Known enteropathogens were not detected in their stools but Escherichia coli displaying aggregative adherence to HEp-2 cells (enteroaggregative E. coli) were found in 12 (63%) ill infants and in none of 5 well neonates (P = 0.02). The illness lasted 3-9 days (mean 5.2) in 16 babies, whereas in 3 neonates it showed a protracted course of 18-20 days. The source of infection and the mode of transmission remained unclear. The outbreak isolates manifested properties common in this new group of diarrhoeagenic E. coli: mannose-resistant haemagglutination, haemolysis on blood agar, and clump formation in liquid culture medium. They belonged to the O4 E. coli serogroup and expressed multiple antibiotic resistance.

Bacterial Adhesion↗
PubMed1977

[Diagnosis of von Willebrand's disease].

Diagnosis and differential diagnosis of von Willebrand's disease was a special problem. Criteria up to date: prolonged bleeding time, reduced platelet adhesiveness, decreased F. VIII coagulant activity, as well as a particularly behaviour after the infusion of F. VIII, were not sufficient to differentiatie this disease from other congenital disorder of F. VIII. Recent investigations, introducing the immunological methods for determination of F. VIII--related antigen, as well as the investigation of ristocetin induced platelet aggregation, give the new approach in the diagnosis of von Willebrand's disease. Authors presented preliminary results of investigations of F. VIII--related antigen in the patients with von Willebrand's disease, as well as the results of investigation of the patients with hemophilia A and normal subjects, as a control group.

Adult↗
PubMed1977

[Immunoelectrophoretic method for the determination of factor VIII-related antigens].

Immunological examination of F VIII related antigen gave some new information on the nature of congenital defects of F VIII, in haemophilia A and von Willenrand's disease. Besides classic method in diagnostics of von Willebrand's disease, the determination of F VIII related antigen can be used as a diagnostic criterium in distinguishing von Willebrand's disease from some mild forms of haemophilis, as well as in detection of haemophilia carrier. In addition, the study on the relationship of immunological value of F VIII related antigen and biological activity of F VIII offers more data on the possibility of detection of so-called "hypercoagulability" and states proceeding thrombosis. The method for determination of F VIII related antigen (Rocket electrophoresis--Laurel) as well as the values of F VIII in health persons of our population is described in this paper.

Antigens↗