[Mean age at death for selected causes of death and the mortality rate in West Germany 1958 and 1978].
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Biomedical subjects
Publications and source records attributed to B Junge.
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In Japan, total mortality of men and women in the age groups of 45-54, 55-64, and 65-74 years decreased, within the last three decades, by 50-60% to values which are now among the lowest in the world. During the same period, death rates of men decreased by approx. 20% in the USA and approx. 10% in the Federal Republic of Germany (FRG). As to women, decreases in both countries were over 30%. The decrease between 1968 and 1978 (period of validity of the 8th Revision of the ICD) in the three countries was mostly due to the diseases of the circulatory system: In Japan, mostly to cerebrovascular diseases, in the USA, to ischaemic heart diseases, and in the FRG, to other forms of heart diseases. Second to the diseases of the circulatory system, stomach cancer and infective and parasitic diseases contributed most to the total decrease in Japan, accidents and diseases of the respiratory system in the USA, and diseases of the respiratory and digestive systems in the FRG. The highest percentage increases of death rates for the specific causes were recorded for lung cancer in all three countries and for other forms of heart diseases in the USA.
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In a comparative study, the differences between the values measured for 26 blood and serum components in both winter and summer were determined in 78 healthy subjects. Comparable conditions during the preparation of test persons, sampling, processing of specimens, and measurement were strictly observed. The term "season" is defined more precisely by meterological data. In the summer season, significantly higher values were found for leukocytes (9%), lactate dehydrogenase and MCHC (7% each), creatinine (7%, in women only), and MCH (1%) whereas significantly lower values were exhibited by aspartate aminotransferase (18%), alanine aminotransferase (14%), alkaline phosphatase (11%), glucose and packed cell volume (7% each), MCV (6%), total protein (2%), erythrocytes, albumin, sodium and chloride (1% each). These partly considerable alterations should be taken into account in the establishment of reference values and evaluation of laboratory findings (above all, when intraindividual comparison is involved). There were no significant alterations of the following parameters: hemoglobin, gamma-glutamyl transferase, urea, uric acid, creatinine (men only), bilirubin, cholesterol, total glycerol, potassium, calcium, and inorganic phosphate. In another series of experiments involving 32 test persons, the influence of different ambient temperatures during blood sampling on the above mentioned blood components was studied. Within the 18-30 degrees C range, no significant alterations were detected.
Trends and regional differences in lung cancer mortality and cigarette smoking are examined for 26 developed countries. "In 1975, lung cancer mortality figures for females aged 55 to 64 years...showed 12 to 60 deaths per 100,000 inhabitants, for males 60 to 270 deaths. In nearly all countries the mortality rates of males have been increasing since 1958.... For females the rise in lung cancer mortality is particularly steep...." An increase in cigarette smoking between 1935 and 1973 is also noted, and it is found that "the ranking of the countries by cigarette consumption essentially corresponds to that by lung cancer mortality." (summary in ENG)
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The extent and dynamics of changes by short (1 min) or prolonged (6 min) tourniquet application while obtaining venous blood samples were analysed with respect ot 33 frequently measured constituents of blood and serum. After 6-minute tourniquet application the values for red cells, haemoglobin, packed cell volume, total protein, albumen, gamma-glutamyl transferase, alkaline phosphatase, lactate dehydrogenase, creatinekinase, bilirubin, cholesterol, total glycerol and calcium increased by an average of 4-9%. One-minute tourniquet application did not have a significant effect. Levels of sodium, potassium, carbon dioxide, creatinine, uric acid, ratio of electrophoretic fractions and the MCV, MCH and MCHC indices were not affected even by 6-minute tourniquet applications. The introduction of blood sampling under standardised conditions is proposed.
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