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Biomedical subjects

B K Ahluwalia

Publications and source records attributed to B K Ahluwalia.

At least 19 recordsLinked to original sources

Evaluation of subconjunctival anaesthesia vs peribulbar anaesthesia in cataract surgery.

A comparative study was carried out to evaluate peribulbar anaesthesia (group A) vs subconjunctival anaesthesia (group B). The results proved peribulbar anaesthesia to be more effective than subconjunctival anaesthesia as regards orbicularis akinesia (p < 0.05) and ocular akinesia (p < 0.05). There was no significant difference in the sensory anaesthesia, analgesia and intraocular pressure changes in the two groups (p > 0.05). Block assessment was ideal in 80% of patients in group A in comparison to 51% in group B (p < 0.05), and unsatisfactory in 14% in group A and 30% in group B (p < 0.05). Further, no significant complications were observed with peribulbar anaesthesia. Therefore, we conclude that peribulbar anaesthesia should be preferred over subconjunctival anaesthesia for conventional extracapsular cataract extraction with or without intraocular lens implantation.

Anesthesia, Local↗

Tear film profile in Graves' ophthalmopathy.

Tear film profile was studied in 30 patients with Graves' ophthalmopathy. Tear film pH, fluorescein staining, marginal tear strip and Schimer test values in patients with Graves' ophthalmopathy were comparable with controls, indicating normal tear secretion. Tear film break-up-time (BUT) in late Graves' ophthalmopathy was significantly low suggesting unstable tear film. Rose bengal as well as lissamine green staining intensity scores were significantly high, indicating presence of drying epithelial cells in early as well as late Graves' ophthalmopathy patients.

Adolescent↗

An experimental model of oculorespiratory reflex.

An experimental study of the oculorespiratory reflex (ORR) was conducted on 20 albino rabbits using a square wave (SW) type of stimulus. The ORR could be elicited in 100% of animals. The medial rectus was observed to be most reflexogenic for ORR. The frequency and pattern of ORR was not affected by bilateral vagotomy, intravenous atropine or glycopyrrolate, but could be completely abolished by retrobular block.

Animals↗

Total lactate dehydrogenase and its isoenzyme pattern in lens, aqueous humour, and serum in cases of senile cataract.

Lens, aqueous humour and serum LDH and its isoenzyme pattern were estimated in 50 patients with senile cataract; 10 each with immature senile cortical cataract, mature senile cortical cataract, hypermature senile cortical cataract, immature senile nuclear cataract and mature senile nuclear cataract. The gradual decrease in total LDH and activity in the lens with advancement of cataract was maximum in hypermature senile cortical cataract. Aqueous LDH and its isoenzyme pattern remained unaltered with the maturity of cataract, and serum LDH and its isoenzyme pattern were found to be within normal limits. The lens LDH activity was found to be not related to the serum and aqueous humour LDH activity, but LDH3 isoenzyme showed declining trend, whereas LDH5 isoenzyme increased with the maturity of cataract. The present study concluded that significant decrease in lens LDH did not bear any relationship to LDH in serum and aqueous humour in cases of senile cataract.

Aged↗

Tear film profile in dry eye.

Tear film profile was studied in 100 consecutive patients with dry eye along with 100 age and sex matched controls. The frequency of abnormal tear function tests observed in patients with dry eye and controls was: marginal tear strip 93% and 11%, rose bengal staining 89% and 0%, lissamine green staining 87% and 0%, BUT 79% and 14%, Schirmer test 79% and 3% and fluorescein staining 69% and 0%, respectively. No significant difference was observed between tear pH of patients with dry eye and that of normal healthy subjects. A new, simple and effective objective criteria of confirming and grading dry eye based upon a points scoring system derived from the results of various tear film tests is suggested.

Adolescent↗

Topical indomethacin for vernal keratoconjunctivitis.

Twenty-five patients with vernal keratoconjunctivitis (VKC) were treated with 1% indomethacin eyedrops and were followed for 5 weeks. Apart from 4 patients all of them showed marked improvement. The possible mechanism of the role of indomethacin in VKC is discussed.

Administration, Topical↗

Tear lysozyme levels in bacterial, fungal and viral corneal ulcers.

Low levels of tear lysozyme were observed in patients with infective corneal ulcers, when compared with controls. Lowest levels were seen in patients with bacterial corneal ulcers. The levels of tear lysozyme showed a corresponding decrease with the increase in Schirmer test values; meaning thereby, that in ocular conditions associated with increased rate of tear flow, the lysozyme content in tears tends to be low.

Adult↗

Serum and tear immunoglobulins in bacterial, fungal and viral corneal ulcers.

Serum and tear IgA, IgG and IgM levels were studied in patients with bacterial, fungal and viral corneal ulcers. In patients with viral corneal ulcers serum IgA and IgG levels were found to be significantly raised, while IgM concentration remained unaltered. In bacterial and mycotic ulcerations, serum IgA, IgG and IgM levels remained unaltered. All three immunoglobulins were found to be raised in tears of patients with viral corneal ulcers, while only IgA levels were found to be increased in bacterial and mycotic ulcerations.

Adult↗

An unusual case of endogenous aspergillus endophthalmitis.

Endogenous aspergillus endophthalmitis is not a common entity. So far, about 25 cases have been reported in the world literature, and to the best of our-knowledge, the crystalline lens was invaded by the fungus in none of the cases, as seen in the present case. This unusual feature, coupled with the rarity of the condition in general, made it worth reporting.

Anterior Chamber↗

Status of cyclopentolate as a cycloplegic in children: a comparison with atropine and homatropine.

We compared the cycloplegic effects of cyclopentolate, homatropine and atropine by the retinoscopy findings and residual accommodation left following their use in the same individual. The mean residual accommodation measured after the use of cyclopentolate, homatropine and atropine was 1.48 +/- 0.33 D, 2.32 +/- 0.37 D and 1.10 D +/- 0.28 D, respectively, and the mean difference in retinoscopy readings between cyclopentolate and homatropine, homatropine and atropine, and atropine and cyclopentolate was 0.46 +/- 0.21, 0.71 +/- 0.23 and 0.26 +/- 0.14, respectively. We further observed that a tonus allowance of about +0.75 D would suffice for cyclopentolate. The merits for recommending cyclopentolate as a routine cycloplegic in children are discussed.

Accommodation, Ocular↗

Study of Duane's retraction syndrome.

The clinical observations made on 20 patients (24 eyes) of Duane's retraction syndrome are presented. A modification of Huber's classification of the syndrome is suggested in order to make it more clinically orientated.

Duane Retraction Syndrome↗

Study of tear film flow and stability in chronic dacryocystitis.

Tear film flow and stability studies were carried out in patients suffering from chronic dacryocystitis by performing Schirmer test-I and tear film break-up-time (BUT) measurements. The results of Schirmer's test corroborated the theory that a reduced out flow of tears causes a compensatory reduced tear secretion. The results of break-up-time confirm the fact that BUT is independent of outflow of tears in patients with epiphora.

Adult↗

Tear film flow and stability in acute and chronic conjunctivitis.

Tear film flow and stability studies were carried out in patients suffering from acute and chronic conjunctivitis by performing Schirmer test-I and break-up-time (BUT) measurements. In this clinical study, patients with chronic conjunctival inflammation demonstrated a premature break-up of tear film despite normal amounts of aqueous tears. In acute catarrhal conjunctivitis the values of BUT were within normal limits, whereas the values of Schirmer test-I were significantly higher (t-test, P less than 0.001) and are considered to be due to reflex hypersecretion of tears.

Adult↗

Primary epitarsus: a case report.

Epitarsus is a rare congenital anomaly or may be acquired following severe conjunctivitis, usually of a cicatrising nature. The terms primary and secondary epitarsus are suggested to denote the two different aetiological varieties. On its clinical and histopathological features the present case conforms to the interfornix variety of primary epitarsus.

Conjunctiva↗

Eccrine spiradenoma of eyelid: case report.

A case report is presented of eccrine spiradenoma, a benign sweat gland tumour which, though not uncommon generally, is rare in the eyelid. The possibility of sweat gland tumour should be kept in mind in the diagnosis of eyelid tumours.

Adenoma, Sweat Gland↗