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Biomedical subjects

B K Bartee

Publications and source records attributed to B K Bartee.

9 recordsLinked to original sources

Extraction site reconstruction for alveolar ridge preservation. Part 1: rationale and materials selection.

Alveolar ridge resorption has long been considered an unavoidable consequence of tooth extraction. While the extent and pattern of resorption is variable among individuals, there is a progressive loss of ridge contour as a result of physiologic bone remodeling. Over the long term, prosthodontic complications, loss of function, and inadequate bone for the placement of dental implants may result. Guided bone regeneration techniques and the use of bone replacement materials have both been shown to enhance socket healing and modify the resorption process. This review describes the process of alveolar bone loss, materials for extraction site grafting, and proposed mechanisms for ridge preservation.

Absorbable Implants↗

Extraction site reconstruction for alveolar ridge preservation. Part 2: membrane-assisted surgical technique.

Alveolar ridge resorption has long been considered an unavoidable consequence of tooth extraction. Guided bone regeneration techniques and the use of bone replacement materials have both been shown to enhance socket healing and to potentially modify the resorption process. This article will describe a surgical technique using textured, high-density polytetrafluoroethylene (PTFE) membrane and particulate bone replacement materials for graft containment and prevention of soft tissue ingrowth into healing extraction sites. The technique described does not require primary closure, facilitating the preservation of keratinized mucosa and gingival architecture.

Alveolar Bone Loss↗

Evaluation of a new polytetrafluoroethylene guided tissue regeneration membrane in healing extraction sites.

The biological principles underlying guided tissue regeneration (GTR) are apparently well understood, and many of the molecular events involved in bone regeneration are being investigated. Much controversy exists, however, as to which membrane biomaterial is ideal for use in these procedures. Adding to the confusion, new applications of GTR membranes continue to evolve, such as extraction site reconstruction, implant site development, ridge augmentation, and the use of membranes in conjunction with the placement of dental implants. These innovative techniques place demands on the membrane that were unforeseen when the first generation of devices was developed. The present study suggests that the ideal design characteristics of a barrier membrane, such as pore size and polymer type, may depend on the intended use of the membrane, and are not fixed criteria that should be applied to all membrane devices. This article describes the clinical results in a series of case studies using a high-density, microporous polytetrafluoroethylene membrane (Cytoplast Regentex GBR-200a). To evaluate the clinical efficacy of this membrane and technique, clinical and histological evaluation of the regenerated tissue are presented.

Biocompatible Materials↗

The use of high-density polytetrafluoroethylene membrane to treat osseous defects: clinical reports.

Alveolar bone resorption can result from tooth loss, periodontal disease, or trauma. Guided tissue regeneration is used in an attempt to exclude tissues devoid of osteogenic potential from a bone defect or cavity and promote new bone growth to replace missing osseous structure. Many types of barrier membranes have been used, but none have been found to be ideal for every clinical situation. Macroporous membranes, such as expanded polytetrafluoroethylene, require primary closure and a second surgical procedure for their removal. Macroporous membranes can incorporate bacteria and may become infected if exposed in the oral cavity. Membranes manufactured of resorbable polymers require primary closure of the augmentation site and exhibit variable patterns of resorption, introducing a degree of unpredictability into the procedure. The use of high-density polytetrafluoroethylene membrane to promote deposition of bone for ridge augmentation in the oral cavity is described. Two clinical reports are presented.

Alveolar Ridge Augmentation↗

Evaluation of a high-density polytetrafluoroethylene (n-PTFE) membrane as a barrier material to facilitate guided bone regeneration in the rat mandible.

The purpose of this investigation was to evaluate the use of high-density polytetrafluorethylene (n-PTFE) membranes to facilitate guided tissue regeneration (GTR) in the rat. The concept of guided tissue regeneration is based on the hypothesis that if the non-osteogenic connective tissue cells are mechanically blocked from entering a bone defect, selective re-population of the defect by osteoblasts will occur. Bilateral through-and-through defects of critical size were created in the mandibular angle of 12 rats. The experimental side was covered on both the medial and lateral aspects of the mandible with high-density n-PTFE membrane, with the opposite side serving as a control. Histological analysis revealed osteogenic tissue completely bridging the defect by two weeks. After six weeks of healing, osteogenic repair was observed at the margins of the defects, with islands of woven bone seen in the central areas. After 10 weeks of healing, complete ossification was observed on the n-PTFE-treated side. The control defects exhibited very little osseous regeneration, and rounding of the defect margins was observed after 10 weeks of healing. These results indicate that high-density n-PTFE can serve effectively as a guided tissue regeneration barrier in certain bone defects.

Animals↗

Reconstruction of an atrophic edentulous maxilla with unilateral cleft lip and palate (UCLP) using sub-antral augmentation and osseointegrated implants: case report and 3-year follow-up.

With the current sophisticated, multidisciplinary approach to the treatment of cleft palate, it is anticipated that most patients with this deformity will enjoy good dental health and function. However, due to the number of older adults who were not treated with primary bone grafting and orthodontic therapy, there remains a significant number of potential candidates who may benefit from dental implants and implant-supported prostheses. Although it was not necessary in this case, a pharyngeal extension may be added to the maxillary denture to further improve speech and deglutition. This case report presents a three-year follow-up of a complex reconstruction of a highly compromised, edentulous patient. Stable fixation of the maxillary prosthesis results in a complete return to function in an individual for whom traditional dental prosthetics had resulted in ten years of failure and frustration. Combining the disciplines of reconstructive surgery and implant prosthetics enables the clinician to achieve a predictable result (Figures 12 and 13). While this case represents an extreme example, there are millions of patients for whom implant dentistry can provide life-changing benefits.

Adult↗

Ridge augmentation with dense hydroxylapatite/resorbable suture matrix.

The atrophic edentulous ridge represents one of the greatest challenges faced in general practice. An estimated 20 million adults in the U.S. are edentulous in at least one arch and a significant number of these patients experience problems with their prostheses from alveolar bone loss. Many of these patients, for various reasons, are not candidates for endosseous dental implants. Alveolar ridge augmentation is a viable option in many of these cases; however, this procedure has been unpredictable because of particle migration. Presented here is a method of ridge augmentation with dense hydroxylapatite beads linked in a resorbable suture matrix to prevent particle migration during healing. This technique may be performed with minimally invasive surgery, providing long-term prosthetic support.

Absorbable Implants↗