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Biomedical subjects

B K Semb

Publications and source records attributed to B K Semb.

At least 55 records · Page 3Linked to original sources
PubMed1980

Gastric cooling and regional gastric mucosal flow in anesthetized animals.

Regional gastric mucosal flow was measured by hydrogen clearance techniques during gastric cooling. At subnormal temperatures a considerable augmentation of mucosal flow was observed both in the antrum and corpus region. At mucosal temperatures below 15 degrees C, which only could be reached by continuous balloon perfusion of the stomach with chilled water, a moderate decrease of mucosal flow occurred in normothermic animals. On the basis of the presented results it appears debatable whether gastric cooling has any place in the treatment of bleeding from gastric mucosal lesions as a means of reducing gastric mucosal flow.

Anesthesia, Intravenous↗
PubMed1980

Regional gastric flow determined by a hydrogen clearance technique in anesthetized and conscious animals.

Gastric microcirculatory studies were performed by a hydrogen clearance technique in anesthetized and conscious cats. The highest flow values were observed in the mucosa, while submucosal flow was higher than muscularis flow. During anesthesia antral blood perfusion exceeded corpus perfusion, but this relationship was reversed in favor of the corpus region in conscious animals.

Anesthesia, General↗
PubMed1979

"Balloon valvulotomy" of congenital pulmonary valve stenosis with tricuspid valve insufficiency.

The rare congenital anomaly of pulmonary valve stenosis and massive tricuspid valve insufficiency with intact ventricular septum is a lethal condition without reported survival after attempted treatment. In a neonate suffering from this syndrome, the pulmonary valve stenosis was relieved by rupturing the fused valve with a balloon catheter introduced transvenously. The desperate condition of the patient quickly improved after this procedure, with subsequent disappearance of the tricuspid valve incompetence. Balloon rupturing of fused valves at angiography may represent a therapeutic alternative in cases in which surgical valvulotomy is associated with a high mortality.

Cardiac Catheterization↗
PubMed1979

Primary results with the new Hall-Kaster disc valve prosthesis in mitral position.

The Hall-Kaster central flow prosthetic heart valve was introduced in 1977 in an attempt to improve the hemodynamics of the disc valve prostheses. Towards this accomplishment, innovations in the tilting axis, the disc guidance mechanisms, and disc translational freedom cooperate to improve flow through both orifice segments of the open valve. The present study reports on the primary clinical and hemodynamic findings in the first 20 patients (mean age 57.6 years) with isolated mitral valvular disease, examined 3--4 months after insertion of the Hall-Kaster disc valve prosthesis. The hemodynamic findings displayed low gradients and high calculated valve areas (5). At rest, the mean diastolic pressure gradient across the smallest prosthesis used (O.D. 27) averaged 3.0 mmHg, vs. 2.6 mmHg across the largest valve sizes (O.D. 29--31). Calculated valve area was on an average 3.08 cm2 for the smaller valve, and 3.47 cm2 for the larger valves, which corresponded to an utilization of 81% and 77% of the orifice area measured in vitro. A comparison with earlier studies of mean diastolic mitral gradients with different mitral prostheses indicates that the Hall-Kaster disc valve represents an improvement towards a hemodynamically more efficient prosthesis for mitral valve replacement.

Aged↗
PubMed1979

Intraoperative and postoperative hemodynamic studies in patients undergoing aortic valve replacement with the Hall-Kaster cardiac disc valve prosthesis.

Intraoperative and postoperative hemodynamic measurements in the first patients to receive the Hall-Kaster cardiac disc valve prosthesis in the aortic position demonstrated the principal hemodynamic pattern of this new mechanical valve. These hemodynamic studies demonstrated favourable transvalvular gradient values and a degree of flow area utilization of the valve orifice which was close to its theoretical maximum. The Hall-Kaster prosthesis thus presented improved flow characteristics in patients undergoing aortic valve replacement, which is considered of particular importance to the patients with a narrow aortic root.

Adult↗
PubMed1979

In vivo haemodynamic evaluation of the Hall-Kaster central flow prosthetic heart valve.

The first in vivo haemodynamic observations of the recently developed Hall-Kaster central flow prosthetic heart valve are reported. Haemodynamic evaluation of valve function was performed both in acute and chronic experiments following implantation of the Hall-Kaster prosthesis in the mitral position in dogs. These studies showed a low transvalvular pressure gradient, an effective opening angle of about 70 degrees and good diastolic flow through both the large and small orifices of the prosthesis. A slow rotational movement was depicted by the disc during opening and closure.

Animals↗
PubMed1979

Gastric flow measured with hydrogen clearance technique.

Regional gastric flow could be measured by hydrogen clearance technique. This method permitted the simultaneous measurement of flow in the mucosa, submucosa, and muscularis of both the antrum and corpus in anesthetized dogs. The main advantage of this method compared with other techniques used for gastric microcirculatory studies is that it offers the opportunity of repeated flow determinations in an anatomically identical area under various experimental conditions.

Animals↗
PubMed1977

Peroperative vasopressin infusion during portocaval shunt surgery.

Intravenous infusion of vasopressin decreased mesenteric arterial- and portal venous flow in dogs. In 4 of 5 high-risk patients, in whom acu te portosystemic shunting was performed, the peroperative intravenous infusion of vasopressin facilitated the surgical procedure by reducing portal pressure and peroperative bleeding from venous collaterals. In 1 patient with reversed portal flow, the portal pressure and flow were not affected by the vasopressin infusion. No undesirable effects of vasopressin were encountered and all patients survived surgery and the early postoperative period.

Adult↗
PubMed1977

Visceral ischaemia following coeliac- and superior mesenteric artery occlusion. Report of a case.

A patient with acute ischaemia of the abdominal organs after coeliac- and superior mesenteric artery occlusion is reported. Following vascular reconstruction and resection of gangrenous colon and ileum the main early postoperative problem was hepatic failure. A grave malabsorption syndrome developed necessitating periodic i.v. hyperalimentation. The patient showed no improvement of intestinal function and died 5 months postoperatively from peritonitis.

Acute Disease↗
PubMed1975

Suture line ulcers after gastric surgery.

Four cases of suture line ulcers after gastric surgery caused by nonabsorbable suture material are presented. The literature is reviewed, and a plea ia made for the use of absorbable suture materials in gastrointestinal surgery.

Adult↗
PubMed1975

The "Barrett syndrome" (the columnar-lined lower oesophagus): an acquired condition secondary to reflux oesophagitis. A case report with discussion of pathogenesis.

A case of the "Barrett syndrome" in a patient with severe ulcerating reflux oesophagitis is reported. Evidence indicating that it is an acquired condition caused by reflux of bile-contaminated gastric juice is presented. The "Barrett ulcer" and the oesophagitis healed following a partial gastrectomy with a Roux-en Y gastrojejunostomy. The substitution of the squamous epithelium of the lower 15 cm of the oesophagus by columnar epithelium of cardia type is apparently irreversible.

Esophageal Stenosis↗