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Biomedical subjects

B K Shurkalin

Publications and source records attributed to B K Shurkalin.

At least 19 recordsLinked to original sources

[Ciprofloxacin and other antimicrobial drugs in the treatment of disseminated peritonitis].

Forty two patients with general peritonitis were treated with ciprofloxacin and combinations of various antimicrobial drugs. Ciprofloxacin had the highest effect on aerobic and anaerobic microbes in the peritoneal cavity which defined the favourable clinical results in all the patients. Moreover, there were observed no disorders in the composition of the normal intestinal microflora which in the end promoted a decrease in the number of the patients with suppuration of the surgical wound.

Adolescent

[Treatment of peritonitis of appendicular etiology].

The authors had 475 patients with appendicular peritonitis under observation. All of them underwent emergency operation and were given antibacterial therapy with metronidazole and agents of the aminoglycoside series. Among 223 patients, the operation on whom was completed by traditional drainage of the abdominal cavity and complete closure of the operative wound, 148 patients developed postoperative complications. Five patients died. In 252 patients, primarily delayed sutures were applied to the wound and drainage of the abdominal cavity was limited. The abdominal cavity was inspected repeatedly in 24 patients with generalized peritonitis and clinical signs of anaerobic nonclostridial infection. Postoperative complications occurred in 87 patients and were limited to suppuration of the wound. One patient died.

Adolescent

[Characteristics of the course of peritonitis in relation to the degree of perforation of the gastrointestinal tract].

An examination and treatment of 80 patients with general forms of peritonitis has shown that the course of the disease is greatly dependent on the character of the bacterial dissemination of the abdominal cavity. A microbiological examination has shown that in all the levels of perforation of the gastro-intestinal tract there are associations of various microorganisms. The most severe course of peritonitis is observed when caused by infection by colonic contents with prevailing anaerobic ++non-clostridial microflora in the exudate. The method of repeated revisions of the abdominal cavity should be used for these forms of peritonitis.

Abscess

[Syndrome of endogenous toxemia in complications of pancreonecrosis].

The authors have performed an investigation of the syndrome of endogenous intoxication in the following complications of pancreatonecrosis: pancreatogenous shock, fermentative and fibrinous-purulent peritonitis, parapancreatic infiltrate, abscesses of the pancreas and phlegmons of the retroperitoneal fat. The most pronounced toxicosis was observed in purulent processes in the pancreas, parapancreatic fat and abdominal cavity.

Adult

[Complications of non-clostridial anaerobic peritonitis].

Under observation there were 71 patients with non-clostridial anaerobic peritonitis, 37 of them having complications--suppurations of operation wounds, phlegmons of the abdominal wall, abscesses of the abdominal cavity, postoperative non-clostridial peritonitis. Fourteen patients died (37.8%).

Abdominal Muscles

[Surgical tactics in anaerobic non-clostridial peritonitis].

Under observation there were 128 patients with neclostridial peritonitis (NP) which made up 19.3% of the total number of patients with peritonitis. In spreaded NP when the source of NP was successfully eliminated and fibrinous layers on the peritoneum the laparotomy wound was tightly sutured up to the aponeurosis (included), primary delayed sutures were put on the skin. When it was impossible to completely remove all the fibrin from the peritoneum, the wound was sutured through all the layers, the sutures were tied in bows followed by numerous revisions of the abdominal cavity. Laparotomy was performed in postoperative NP with phlegmons of the abdominal cavity. The use of the tactics described allowed lethality to be reduced from 39.4% to 13.7%.

Anti-Infective Agents, Local

[Indicators of general toxemia in diffuse peritonitis].

Methods of determination of general toxicity are thought to be necessary to obtain higher efficiency of treatment of patients with peritonitis. They facilitate the establishment of indications for choice of methods of the complex detoxicating therapy. Using the method of determination of the concentration of toxic middle mass metabolites gives an objective assessment of the degree of the endogenic intoxication syndrome.

Hemoperfusion