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Biomedical subjects

B Kang

Publications and source records attributed to B Kang.

At least 55 records · Page 3Linked to original sources
PubMed1994

Sonographic diagnosis of acute hematogenous osteomyelitis in the early stage.

This article presents sonographic diagnosis of acute hematogenous osteomyelitis in early stage. 24 children with clinically suspected acute hematogenous osteomyelitis were detected to have subperiosteal abscesses by ultrasound during four to fourteen days after onset. The mean length and anteroposterior distance of the subperiosteal abscesses were 86.4 mm and 10.7 mm, respectively. Of 24 cases of subperiosteal abscesses, aspiration performed under ultrasound guidance revealed purulent fluid in all and 23 were verified surgically. The results obtained indicate that ultrasound can be used in diagnosis of acute hematogenous osteomyelitis in the early stage. The earliest case was diagnosed by ultrasound 4 days after onset. By use of ultrasound, differentiation diagnosis of acute hematogenous osteomyelitis from other diseases such as cellulitis, soft tissue abscess, acute septic arthritis and malignant bone tumors is also discussed.

Acute Disease↗
PubMed1994

L-NAME modulates responses to adrenomedullin in the hindquarters vascular bed of the rat.

Responses to synthetic human adrenomedullin (ADM), a novel hypotensive peptide recently discovered in human pheochromocytoma cells, and calcitonin gene-related peptide (CGRP), a structurally related peptide, were investigated in the hindquarters vascular bed of the rat. Under conditions of controlled hindquarters blood flow, intraarterial injections of ADM (0.01-0.3 nmol) and of CGRP (0.03-0.3 nmol) caused dose-related decreases in hindquarters perfusion pressure and decreases in systemic arterial pressure. Following administration of the nitric oxide synthase inhibitor, N omega-nitro-L-arginine methyl ester (L-NAME), hindquarters vasodilator and systemic depressor responses to ADM were significantly decreased, whereas L-NAME did not significantly decrease the vasodilator response to CGRP in either the hindquarters or systemic vascular beds. Following administration of the cyclooxygenase inhibitor, meclofenamate, vasodilator responses to ADM and to CGRP were not significantly decreased. When the relative vasodilator activity of the two peptides was compared on a nmol basis, responses to ADM were similar to responses with CGRP in the hindquarters vascular bed, whereas ADM was 30-100 fold less potent than CGRP in decreasing systemic arterial pressure. The present data demonstrate that ADM has significant vasodilator activity in the hindquarters vascular bed of the rat, that hindquarters vasodilator and systemic vasodepressor responses to ADM, but not to CGRP, are dependent upon the release of nitric oxide from the endothelium.

Adrenomedullin↗
PubMed1994

Sonographic diagnosis of the knee effusion.

This paper presents the diagnosis of effusion of the knee by ultrasound. 140 patients with pain and swelling of the knee were detected to have suprapatellar effusion by ultrasound. The antero-posterior distances of the suprapatellar effusion were 0.2-3.4 cm with a mean of 1.2 cm. The effusion was revealed as an anechoic fluid-filled area in 121 cases (86.4%), as a hypoechoic area in 15 cases (10.7%), and as a mixed anechoic fluid-filled area and hypoechoic area in remaining 4 (2.9%). Of 140 cases of knee effusion, 126 cases were verified by aspiration or operation. The results obtained demonstrate that ultrasound can visualize not only the effusion of the knee, but also the abnormalities in the menisci, synovium, and the popliteal fossa; This provides an important basis for diagnosis and treatment. Furthermore, ultrasound is painfree, noninvasive, inexpensive, readily acceptable by patients, and convenient for follow-up studies.

Adolescent↗
PubMed1993

Ultrasound diagnosis of effusion of the hip.

This paper reports on two prospective studies of ultrasound examination of the hip in 150 healthy subjects and 50 patients with hip joint diseases. The sagittal distance of the anterior recess of the hip was measured on the sonogram of the sagittal section. The normal value in adults, teenagers and children was 4.54 mm +/- 0.99 mm, 4.27 mm +/- 1.26 mm and 3.40 mm +/- 0.93 mm, respectively. Ultrasound examination of both hips in 50 patients with hip joint diseases showed that the sagittal distance of the anterior recess was significantly widened in the symptomatic side, and the mean value in the symptomatic side and normal side was 12.02 mm +/- 3.68 mm, and 4.12 mm +/- 1.15 mm, respectively. Ultrasound showed echo-free area in anterior recess in 42 hips, hypoecho and medium echo area in 8 hips. Of 50 patients undergoing plain radiography, 33 showed bony changes of the hip, and the remaining 17 no change whatever. The results obtained demonstrated that ultrasound can accurately detect effusion of the hip, what is more, it is easy to operate, inexpensive, noninvasive, convenient for follow-up and without radiation damage.

Adolescent↗
PubMed1993

Sonographic diagnosis of intramuscular hemangiomas.

This article reports 10 cases of intramuscular hemangiomas diagnosed by ultrasound. The results obtained demonstrated that the intramuscular hemangiomas were revealed sonographically as a spindle-shaped or ellipse-shaped mass with a mixed echo structure in the skeletal muscle, and usually with small calcifications. The solid parts of the tumor most commonly have a medium echogenicity, but few hyperechogenicity. The cavity or sinus containing blood has a hypoecho or echo-free structure.

Adolescent↗
PubMed1993

[Effect of suo quan pill for reducing clozapine induced salivation].

UNLABELLED: 40 Schizophrenic inpatients with clozapine induced salivation were divided into two groups randomly. They were treated with Suo Quan pill and a control study of the placebo (neutral pill) for reducing clozapine induced salivation. These cases were also classified by TCM Syndrome Differentiation and laboratory examinations were performed. RESULTS: There was a significant difference in effect on salivation between the therapeutic group (21 cases) and the controlled group (19 cases), P < 0.01. According to their TCM subtypes two subtypes (Stagnation of Phlegm-Dampness and Yin Deficiency) showed the best results. No correlation between the peripheral clozapine level and salivation was found. No side effect was recorded.

Adult↗
PubMed1989

Histochemical localization of mushroom tyrosinase in whole tissue sections on nitrocellulose.

Mushrooms were cut into vertical and horizontal sections. These sections were blotted onto nitrocellulose sheets and the sheets were then stained for tyrosinase using L-dopa. Tyrosinase was localized throughout the mushroom tissues but more enzyme was located in the epidermis of the cap, the gill region, and the stipe. Preincubation of the nitrocellulose sheets in specific inhibitors of tyrosinase completely blocked enzyme staining, suggesting that the enzyme stained areas on the nitrocellulose blots were regions of tyrosinase activity. Immunochemical localization of tyrosinase was similar to that observed by histochemical staining. Nitrocellulose blotting of mushrooms allows localizations of enzyme at the whole tissue level and may be useful for other enzymes in mushrooms as well.

Basidiomycota↗
PubMed1985

Anion carrier in the human erythrocyte exists as a dimer.

The in situ state of assembly of the human erythrocyte anion carrier (band 3) has been investigated by applying target size analysis on the radiation-induced inactivation of anion flux and degradation of polypeptide band 3. Irradiation with a high energy electron beam resulted in inactivation of carrier-mediated anion flux in intact cells, in inside-out vesicles devoid of cytoskeletal and cytoplasmic proteins, and in inside-out vesicles whose band 3 protein has been partially proteolyzed, with little change in leak pathway. The inactivation showed a single exponential function of radiation dose from which the target size of the anion carrier was estimated to be 210,000, 220,000, and 98,000 daltons in intact cells, in the inside-out vesicles, and in the vesicles after a limited proteolysis, respectively. Irradiation also resulted in degradation of the band 3 of the inside-out vesicles, as detected on sodium dodecyl sulfate-gel electrophoresis, with a dose dependence characteristic of a target size of 220,000 daltons. It is suggested that the human erythrocyte anion carrier exists in situ as a dimer of band 3.

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid↗
PubMed1982

Successful treatment of far-advanced progressive systemic sclerosis by D-penicillamine.

A 52-yr-old man had chronic recurrent pseudo-obstruction of the colon, along with multisystem disease secondary to progressive systemic sclerosis (PSS). D-Penicillamine treatment reversed the PSS, which involved the duodenum, small and large intestines, lungs, myocardium, and proximal and peripheral skin. The improvement was documented by electrocardiogram pulmonary function studies, roentgenography of gastrointestinal tract, and by repeated skin biopsies. Hand blood-volume studies using 99m Tc also revealed improvement of PSS in both hands. A variable degree of improvement was documented in seven additional patients with PSS. Follow-up periods were 18 mo to 4 yr. The most common side effect of the drug was transient hypogeusia, and no patient showed a serious side effect. This article includes a review of the literature on penicillamine therapy for PSS.

Adolescent↗