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Biomedical subjects

B Kolmodin-Hedman

Publications and source records attributed to B Kolmodin-Hedman.

9 recordsLinked to original sources
PubMed1979

Long-term exposure to electric fields. A cross-sectional epidemiologic investigation of occupationally exposed workers in high-voltage substations.

In the present epidemiologic study, 53 workers with a long-term (more than five years) exposure to the electric field of 400 kV substations were examined and compared with a matched reference group of 53 nonexposed workers from the same power companies. Matching variables included age, geographic location and employment time. The aim of the study was to investigate the possibility of persistent, chronic health effects in the exposed group as a consequence of exposure. The investigation indluded the nervous system (neurasthenic symptoms, psychological tests, electroencephalography), the cardiovascular system (symptoms, blood pressure, electrocardiography), and the blood (hemoglobin, red blood cells, reticulocytes, white blood cells including differential count, thrombocytes, sedimentation rate). Fertility was also assessed. The results showed no differences between the exposed and reference groups as a consequence of the long-term exposure to the electric fields. The groups differed, however, in that the exposed group had (a) consistently better results on the psychological performance tests, (b) a fewer number of children, especially boys, and (c) somewhat higher education. The differences in test results were due to the higher education among the exposed. The difference in number of children was also thought to be related to factors other than exposure since it was found to be present already 10--15 years before the work in 400 kV substations began.

Adult↗
PubMed1979

Percutaneous absorption of DDT from a parasiticide used for treatment of scabies.

Moderately to markedly increased plasma concentrations of DDT and its major metabolite DDE were found in 3 boys 4, 7 and 9 years of age and also in a 50-year-old woman who, because of suspected or proven scabies infection, had all repeatedly received between 7 and 200 applications of Tenutex (a DDT-containing scabicide) during recent years. Normal values were found in 4 untreated children and in 2 children who had been treated with Tenutex four and three times respectively. In 9 adults there was no significant increase in the plasma concentrations of DDT and DDE after a single 24-hour treatment with Tenutex. These results indicate that DDT, a known constituent of the scabicide Tenutex, can be percutaneously absorbed and lead to measurably increased plasma concentrations after repeated application, especially in children.

Administration, Topical↗
PubMed1978

Effect of occupational exposure to organophosphorus insecticides on neuromuscular function.

Neurophysiological investigations and determinations of cholinesterase activity on plasma and erythrocytes were carried out on 11 Swedish spraymen exposed to bromophos, diazinon, dursbane, and malathion. Plasma cholinesterase activity was significantly reduced after work, while erythrocyte cholinesterase activity was unchanged. In none of the workers with a decreased plasma cholinesterase activity after work could any related acute neuromuscular disturbance be detected when the men were tested with repetitive nerve stimulation and with single fiber electromyography. Signs of subclinical neuropathy were present as a slight reduction in sensory conduction velocity and increased fiber density in some workers.

Action Potentials↗
PubMed1977

Chromosome aberrations and sister-chromatid exchange in workers in chemical laboratories and a rotoprinting factory and in children of women laboratory workers.

Cultured lymphocytes from 73 workers in chemical laboratories and the printing industry were found to have a significantly increased frequency of chromatid and isochromatid breaks, in comparison with 49 control subjects (42 adults and 7 children). An increase of the same magnitude was also found in 14 children, aged 4 days--11 yr, of 11 women laboratory workers who had worked during pregnancy. A significant correlation between age and frequency of chromosome aberrations was noted for both the exposed and control children but not for the adults. The frequency of sister-chromomatid exchange was significantly increased in 12 technicians working in laboratories performing hormone analysis. 4 children of 2 female technicians working during pregnancy also had a significnatly increased frequency of sister-chromatid exchange. The cause and biological significance of these findings are not yet known.

Adolescent↗
PubMed1977

Decrease in alpha-lipoprotein cholesterol in men after cessation of exposure to chlorinate hydrocarbon pesticides.

Eight men who in 1970 had been exposed to chlorinated pesticides and for whom the exposure had ceased in 1976, showed a significant fall in alpha-lipoprotein (HDL) cholesterol between these years. The cholesterol concentration of the other lipoprotein classes showed no significant trend. The data support our previous suggestion that exposure to chlorinated pesticides, mainly lindane, may raise the alpha-lipoprotein levels.

Cholesterol↗