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Biomedical subjects

B Korczakowska

Publications and source records attributed to B Korczakowska.

6 recordsLinked to original sources

[Residues of chlorinated hydrocarbons in livers of newborns, infants and children].

In the liver of 4 newborns, 2 infants and 2 children the levels of residues of chlorinated hydrocarbons were determined. The highest levels of sigma HCH (817 mcg/kg of fat, 17.1 mcg/kg of tissue) were found in a 2-day-old newborn, the lowest ones (43 mcg/kg of fat, 1.8 mcg/kg of tissue) were in an infant aged 12 months. The content of sigma DDT was highest (3044 mcg/kg of fat, 93.8 mcg/kg of tissue) in the liver of an infant aged 13 days, the lowest values (322 mcg/kg of fat, 5.6 mcg/kg of tissue) in the liver of a child aged 12 years. The results are comparable to those obtained in this country in the liver of adults and in human placenta.

Child↗

[Lead contents in liver and kidney of inhabitants of the city of Białystok and vicinity].

The material comprised liver and kidney samples collected from inhabitants of the city of Białystok and of its vicinity during anatomopathological examination at the Department of Pathological Anatomy, Medical Academy in Białystok. In age groups: 2 days-8 years, 29-65 years, 66-84 years, the mean liver lead content was 0.220, 0.211 and 0.233 mg/kg, respectively. The mean kidney lead content amounted to 0.272, 0.038 and 0.125 mg/kg, respectively. When compared with the literature data for subjects not exposed to lead, the present results have to be regarded as low. The newborn displayed a higher kidney lead level than adults. In contrast to adults, in the newborn the content of lead in the kidney exceeded that in the liver. Adults showing a higher lead level in the liver than in the kidney exhibited a correlation between Pb level in the liver and kidney (r = 0.671).

Adult↗

[Rapid method for isolating polychlorinated diphenyls from fat].

Clophen A-60 was isolated from trioleate by a modification of the method of Veierov and Aharonson. In comparison with the original method the change included the replacement of the glass set for separation of the organic phase with Hehner's cylinder, and in place of petrol ether n-hexane was used. The reproducibility of the method at two levels of fortification was high--the variability index at ICB level 0.200 mg/kg was 4.5% and at ICB level 1000 mg/kg was 6.8%. The calculated relative percent error was at the lower fortification was 3.6% on average, and 7.8% at the higher fortification. In view of the short time necessary for the test, low cost, very good degree of purification, high precision and accuracy this method may be used for separation of polychlorinated diphenyls from fats.

Fats↗

[Chlorinated hydrocarbon residues in the adipose tissue of the population of BiaŁystok and its environs].

In the perirenal fat tissue of 36 representatives of this population (20 men and 16 women aged 41 to 92 years) the levels were determined of the residues of alpha-, beta-, and gamma-HCH, DDE, DDD, DDT and sigma DDT. The obtained mean values were 0.012, 0.013, 0.007, 1.421, 0.035, 0.327 and 1.783 mg/kg of fat, respectively. The obtained results were severalfold lower than those found in Poland in the 1970s. The fat of the human fat tissue contained high amounts of beta-HCH as compared to other isomers of hexachlorocyclohexane, and high amount of DDE in sigma DDT. In the fat of men the residues of DDE and sigma DDT were present in greater amounts than in women. On the other hand, no effect of age was noted on the levels of the residues of chlorinated hydrocarbons in human fat.

Adipose Tissue↗

[Chlorinated hydrocarbon residues in the livers of the population of Białystok and its environs].

In the livers of 34 subjects living in Białystok and environs the residues of chlorinated hydrocarbons were determined. The mean values of alpha-HCH, beta-HCH, gamma-HCH, DDE, DDD, DDT and sigma DDT were respectively 16, 60, 81, 1090, 94, 177 and 1361 mcg/kg of fat, and 0.5, 3.2, 3.3, 48, 5.0, 7.1 and 60 mcg/kg of tissue. The content of DDE and sigma DDT in liver fat was similar to that found previously in perirenal fat. In relation to perirenal fat the content of DDT in liver fat was lower and that of DDD was higher. This was due, probably, to metabolic changes taking place in the liver. The relationship between beta-HCH and gamma-HCH in the liver was different from that in fatty tissue in which the level of Indian was lower than that of the beta-isomer.

Adipose Tissue↗