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Biomedical subjects

B Kovalerchuk

Publications and source records attributed to B Kovalerchuk.

4 recordsLinked to original sources

The reliability issue of computer-aided breast cancer diagnosis.

This paper introduces a number of reliability criteria for computer-aided diagnostic systems for breast cancer. These criteria are then used to analyze some published neural network systems. It is also shown that the property of monotonicity for the data is rather natural in this medical domain, and it has the potential to significantly improve the reliability of breast cancer diagnosis while maintaining a general representation power. A central part of this paper is devoted to the representation/narrow vicinity hypothesis, upon which existing computer-aided diagnostic methods heavily rely. The paper also develops a framework for determining the validity of this hypothesis. The same framework can be used to construct a diagnostic procedure with improved reliability.

Breast Neoplasms↗

Prototype Internet consultation system for radiologists.

The overall purpose of this study is to develop a prototype radiological consultation system. We concentrate our work on prototype software environment for the system. The system provides a second diagnostic opinion based on similar cases, incorporating the experience of radiologists, their diagnostic rules and a database of previous cases. The system allows a radiologist to enter the description of a particular case using the lexicon such as BI-RADS of American College of Radiology and retrieve the second diagnostic opinion (probable diagnosis) for a given case. The system also allows a radiologist to get other important information too. These advances are based on a new computational intelligence technique and first-order logic. We implemented a rule-based prototype diagnostic system. Two experimental Internet versions are currently available on the web and are under testing and evaluation of design. The diagnosis is based on the opinions of radiologists in combination with the statistically significant diagnostic rules extracted from the available database.

Breast Diseases↗

Fuzzy logic in computer-aided breast cancer diagnosis: analysis of lobulation.

This paper illustrates how a fuzzy logic approach can be used to formalize terms in the American College of Radiology (ACR) Breast Imaging Lexicon. In current practice, radiologists make a relatively subjective determination for many terms from the lexicon related to breast cancer diagnosis. Lobulation and microlobulation of nodules are two important features in the ACR lexicon. We offer an approach for formalizing the distinction of these features and also formalize the description of intermediate cases between lobulated and microlobulated masses. In this paper it is shown that fuzzy logic can be an effective tool in dealing with this kind of problem. The proposed formalization creates a basis for the next three steps (i) extended verification with blinded comparison studies. (ii) the automatic extraction of the related primitives from the image, and (iii) the detection of lobulated and microlobulated masses based on these primitives.

Breast Neoplasms↗