PubMed Health⌕ Search

Biomedical subjects

B Krüger

Publications and source records attributed to B Krüger.

At least 55 records · Page 3Linked to original sources
PubMed1985

[The bioavailability of combination preparations of acetylsalicylic acid and codeine phosphate].

Plasma levels time curves of acetylsalicylic acid, salicylic acid, salicyluric acid and codeine were monitored after intravenous, oral and rectal application (single dose) of preparations containing acetylsalicylic acid and codeine. The mean absolute bioavailability of acetylsalicylic acid was 68% after oral application and 60% after rectal application. The corresponding bioavailability data of codeine were 59% and 63%, respectively.

Administration, Oral↗
PubMed1983

Are axillofemoral bypass grafts worthwhile? A 10-year review.

Axillofemoral grafts (144 prostheses: 103 unilateral, 25 bifemoral = y-shaped, and 8 bilateral) were performed in a total of 136 patients with aortoiliac occlusion. The average patient was 69 years old. Surgery was indicated only in "high-risk patients" in either stage II (n = 7; walking distance until onset of pain less than 50 m), stage III (n = 55), or stage IV (n = 74). Early occlusion of the prosthesis occurred in 26 cases; 15 were treated successfully by remedial surgery. The total rate of infection after first and remedial operations was 9.7%. The amputation rate, both early and late, was 19%. The early results showed that 114 patients had reached stage II (walking distance until onset of pain over 100 m). The postoperative follow-up period of up to 116 months (average 27.6 months) revealed that the implanted prosthesis had remained patent in 80% of each group of patients at different postoperative intervals. This is extraordinary considering their length and course. Four fifths of the patients lived an average of 22 months, remaining in stage II without loss of limb(s); we believe it made their life more worth living. We conclude that axillofemoral grafts yield satisfactory results for a selective group, namely the "high-risk patient" with aortoiliac occlusion.

Arterial Occlusive Diseases↗
PubMed1981

[Speech audiometry in advanced age - differentiating between the elements of primary and secondary presbyacusis (author's transl)].

Tone threshold, speech intelligibility by the Freiburg test with loss of hearing for speech, discrimination loss and total word intelligibility, dichotic discrimination and binaural summation ability were all measured in 167 test subjects aged between 65 and 91 years. The statistical processing of the numerous parameters shows that all parameters manifest a worsening of hearing with age, the individual values revealing a considerable scatter. Tone loss proved to be largely cochlear in nature. All the speech audiometric parameters correlated highly significantly (binaural summation significantly) with age, in the sense that increasing was accompanied by a worsening of the hearing ability. The complex correlations among all the hearing parameters lead us to believe that ageing affects the organ of hearing as a whole, and not merely specific parts of the auditory pathway. A possibility for differentiating between the elements of primary and secondary presbyacusis, and for measurement of the biological age of the sense organ, ear, is discussed.

Age Factors↗
PubMed1975

[Fetomaternal transfusion in abortion and pregnancy interruptions and Rh-prevention].

The present paper is intended to assess the amount of fetomaternal transfusion in the first and second half of pregnancy, in the peripartal phase as well as in abortion and interruption. The findings of our investigations show that the obtained values of HbF cell invasion approximately correspond to the invasion values in the postpartal phase and call for general immunoprophylaxis in Rh-negative women.

Abortion, Incomplete↗