Evidence for two mechanisms for DNA unwinding catalyzed by DNA helicases.
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DNA Helicases↗
Biomedical subjects
B Kuhn
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DNA helicases.
In summary, we postulate that DNA unwinding and ATP dephosphorylation are coupled in different ways, depending on whether the fibrous ATPase or one of the globular ATPases provides the catalytic agent. Unanswered is the question of whether there is stoichiometry of ATP utilization during the unwinding of a duplex, and unsolved is the role of the individual enzyme in the cell.
Adenosine Triphosphatases↗
Red-cell uridine-5-monophosphate kinase (UMPK): formal genetics, linkage analysis and population genetics from southwestern Germany.
In a population sample from southwestern Germany the frequency of UMPK1 was estimated to be 0.949. The segregation of the children's phenotypes is in agreement with the formal model: 2 common alleles UMPK1 and UMPK2 at an autosomal locus. Data on linkage relations are referred.
Adult↗