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Biomedical subjects

B L Carter

Publications and source records attributed to B L Carter.

At least 19 recordsLinked to original sources
PubMed1979

Computed tomography of spinal fractures.

Computed tomography (CT) has aided significantly in the diagnosis and management of spinal fractures. The examination is easy, relatively quick, and avoids potentially harmful manipulation. The diagnostic advantages of CT include precise anatomic delineation and indication of extent of fractures, assessment of spinal stenosis, and demonstration of associated peraspinal lesions.

Adult↗
PubMed1979

Regulation of cell size in the yeast Saccharomyces cerevisiae.

For cells of the yeast Saccharomyces cerevisiae, the size at initiation of budding is proportional to growth rate for rates from 0.33 to 0.23 h-1. At growth rates lower than 0.23 h-1, cells displayed a minimum cell size at bud initiation independent of growth rate. Regardless of growth rate, cells displayed an increase in volume each time budding was initiated. When abnormally small cells, produced by starvation for nitrogen, were placed in fresh medium containing nitrogen but with different carbon sources, they did not initiate budding until they had grown to the critical size characteristic of that medium. Moreover, when cells were shifted from a medium supporting a low growth rate and small size at bud initiation to a medium supporting a higher growth rate and larger size at bud initiation, there was a transient accumulation of cells within G1. These results suggest that yeast cells are able to initiate cell division at different cell sizes and that regulation of cell size occurs within G1.

Ammonium Sulfate↗
PubMed1978

The yeast nucleus.

Explore the source record for details and available documents.

Cell Division↗
PubMed1978

Computed body tomography: how useful is it?

Computed tomography (CT) of the body is becoming as well established a diagnostic procedure as CT of the head, often yielding information not available by other techniques and sparing patients unnecessary surgery. To take proper advantage of CT, physicians should understand the full potential and practical applications of this new technique. Properly used, it can expedite diagnosis and decrease the number of procedures needed per patient.

Biliary Tract Diseases↗
PubMed1978

Computed tomography in diagnosis of abdominal masses in infancy and childhood. Comparison with excretory urography.

Computed tomography (CT) of the abdomen and pelvis was performed in 26 instances of suspected mass in 24 infants and children. The information obtained was compared to that of standard abdominal radiography and excretory urography (IVP). Results were analyzed prospectively. CT was able to detect and define masses more precisely than abdominal radiography and IVP. The information obtained by CT, in a single noninvasive examination emitting minimal ionising radiation, seems comparable to that offered by a combination of multiple radiological and other imaging procedures. It is conceivable that with accumulating experience and further technological improvement CT may become an excellent screening procedure in the investigation of abdominal and pelvic masses. The high cost of CT scanning may be offset by the benefits cited.

Abdominal Neoplasms↗
PubMed1978

Mediastinal lipomatosis. CT confirmation of a normal variant.

Mediastinal lipomatosis is a common benign cause of mediastinal widening. While it may be associated with exogenous obesity, steroid ingestion, or Cushing's syndrome, these factors often are not present. Evaluation of the mediastinum by CT should be the initial diagnostic study in the work-up of patients with abnormalities of the mediastinal contour; indeed, in many cases it can eliminate the need for other procedures.

Adult↗
PubMed1978

Effects of temperature and nutritional conditions on the mitotic cell cycle of Saccharomyces cerevisiae.

Yeast cells were cultivated at different growth rates in a chemostat by alterations in the flow of the limiting nutrient glucose and in batch cultures where variations in growth rate were achieved by alterations in the composition of nutrients. It was observed that the stage in the cycle at which S-phase was completed varied with growth rate. The faster the growth rate, the earlier the stage in the cycle in which completion of S-phase occurred. When stage in the cycle is converted into time before division it was observed that the time from completion of S-phase to cell division varied only slightly with growth rate except at extremely slow growth rates. Expansion of cell cycle transit time as the growth rate was slowed was achieved primarily by an expansion in time of the period from division to the completion of S-phase. In contrast, when cells were grown at different rates by alterations in the temperature of cultivation, completion of S-phase occurred at approximately the same stage in the cell cycle at all growth rates.

Cell Cycle↗
PubMed1978

Value of computed tomography in radiotherapy of lung cancer.

The effectiveness of CT scanning in radiotherapeutic treatment planning was evaluated in 32 patients with bronchogenic carcinoma. CT of the chest in pretreatment evaluation of these patients supplemented conventional clinical and radiographic patients supplemented conventional clinical and radiographic studies, resulting in (1) more clear delineation of tumor extent in 24 patients (75%); (2) change in assessment of the size of lesions in 14 patients (43%); (3) change of disease stage in 13 (40%); (4) demonstration of inadequacy of treatment plan in nine (28%); and (5) changes in the volume of normal tissue irradiated in 14 (40%). CT scan data was judged essential for treatment planning in 17 patients studied (53%). Unsuspected areas of tumor involvement were seen in 21 patients (65%). Use of the CT scan as a patient contour for radiotherapy treatment planning of lung cancer and alternative techniques are discussed.

Adult↗
PubMed1978

Contribution of computed tomography to the treatment of lymphomas.

The effectiveness of computed body tomography (CT) in the workup, treatment planning, and follow-up of 38 patients with Hodgkin's disease and 59 with non-Hodgkin's lymphoma was analyzed. CT scanning can frequently define lymphoma in the retroperitoneum, and occasionally in mesenteric lymph nodes, spleen, and liver. These data are useful for staging, for radiotherapy treatment planning, and in monitoring response to radiotherapy or chemotherapy. CT was found to be particularly useful in patients with large mediastinal masses. Analysis of patterns of intrathoracic spread allowed modification of treatment techniques in 60% of patients with spread along the chest wall, in order to reduce the volume of normal tissue irradiated, while obtaining adequate dose distributions within the tumor volume. It is anticipated that chest CT scanning in lymphoma patients will lead to improved tumor control and reduction of radiation complications.

Adult↗