[Nikolaĭ Ivanovich Morozkin (on the centenary of his birth)].
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Biomedical subjects
Publications and source records attributed to B L Ugriumov.
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The paper presents clinicoepidemiological characteristics of VHB associated forms in case of parenteral entry of the infection. This predetermines systemic dissemination of the virus. The preventive measures are discussed.
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The paper discusses problems of the prevention and treatment of fulminant hepatitis running with massive and submassive hepatic necrosis in evidence of immunodeficiency. The occurrence of most cases is associated with parenteral mode of the infection entry, violation of antiepidemic regulations in hospitals and lack of donors' supervision. High mortality persisting in hospitals requires urgent measures to control parenteral infection with viral hepatitis of different antigenic variants.
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It is stated that social and scientific progress in the course of evolution gives rise to marked changes in infectious pathology. The changes are obvious from reduced incidence of epidemic diseases, distinct clinical appearance of infection, different cyclic pattern of a number of nosological entities. Such newly recognized diseases as hemorrhagic fever, adenovirus and herpes virus infections, yersiniosis, rotavirus gastroenteritis, legionellosis, AIDS have advanced to the forefront. Previously unknown affections are likely to emerge in various areas of the world and become prevalent in extreme conditions. In addition to virological and immunological examinations, differential diagnosis of the above infections should include a comprehensive analysis of medical histories and clinicoepidemiological evidence in order to provide early detection, hospitalization, high therapeutic response.
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