PubMed Health⌕ Search

Biomedical subjects

B Larson

Publications and source records attributed to B Larson.

At least 55 records · Page 3Linked to original sources
PubMed1990

Reappraisal of uterine sarcoma diagnosis in the Swedish Cancer Registry.

An investigation of over- and under-registration of uterine sarcomas in the Swedish Cancer Registry during the period 1958-1980 was carried out. A histopathologic review of a 10% sample (159 cases) revealed that 18% of the cases, the majority of which were benign leiomyomas, could not be reclassified as sarcomas. All 186 cases of uterine sarcoma treated at Radiumhemmet during the period 1958-1980 were found in the Cancer Registry, but only 90% as sarcomas. As a consequence of over- and under-registration of the sarcoma tumors, the estimated incidences will be affected. In this study, however, we could not find any time trend in the erroneous registration, which implies that comparisons in incidence over time would still be valid.

Diagnostic Errors↗
PubMed1990

Prognostic factors in uterine leiomyosarcoma. A clinical and histopathological study of 143 cases. The Radiumhemmet series 1936-1981.

One hundred and forty-three patients with uterine leiomyosarcomas treated at Radiumhemmet from 1936 through 1981 were reviewed. Clinical and histopathological findings were analysed by bivariate and multivariate analyses to assign prognostic factors. Mitotic count, menopausal status and stage showed to be significant predictors of survival. The series was divided into two periods of time and a significantly higher survival rate in the second period was noted for patients with stage I disease. Thirty-seven patients with tumors showing less than 10 mitotic figures per 10 high power fields had a 5-year survival rate of 65% compared with 17% for 106 patients with 10 or more mitotic figures per 10 high power field. No significant predictor of a bad outcome for these low mitotic count tumors was found.

Female↗
PubMed1989

Aging: the lived experience.

This exploratory study examined the lived experience of aging in a group of 32 community dwelling adults aged fifty to eighty years (M = 68.4). Respondents completed in-depth interviews in which they described the meaning of aging, the "types of things" associated with aging in themselves and in others, and methods of coping with aging-related changes. Respondents' overall impressions of the meaning of aging were generally positive; however, the changes they associated with aging, both in themselves and in others, were almost uniformly negative. Five categories of coping activities were reported: compensation, stress management, maintenance, involvement with others, and alteration in meaning. In general, respondents reported high levels of satisfaction and effectiveness with respect to their coping activities. These findings suggest that individuals who believe they are coping successfully see aging as a positive period in their lives, despite the presence of a significant number of negative changes in themselves and in people close to them.

Adaptation, Psychological↗
PubMed1987

Fracture and ischemic necrosis of the immature scaphoid.

The progressively ossifying scaphoid of the child is well protected but is not immune to injury. The diagnosis of scaphoid fracture may be difficult when the fracture occurs through the osteochondral interface. Nonunion and ischemic necrosis of the proximal pole fragment--complications more often seen in adults sustaining scaphoid fracture--may occur in children, as shown by the young patient presented here.

Carpal Bones↗
PubMed1987

Traumatic longitudinal disruption of the carpus.

Traumatic longitudinal disruption of the carpus is a rare injury that usually occurs through a weak point between the third and fourth metacarpals and the capitate and hamate. Three cases are reported; all injuries were work related and occurred with a broad crushing injury to the hand and wrist. Two patients were treated by fasciotomies, a carpal tunnel release, and excision of a fractured hook of the hamate. The third patient was treated with carpal tunnel release and percutaneous pinning of a wide diastasis. Despite the return of wrist motion, pinch and grip strength remained below normal range in all three patients at follow-up examinations.

Accidents, Occupational↗
PubMed1985

Indications for vitrectomy in congenital retinoschisis.

Two patients with congenital retinoschisis developed rhegmatogenous retinal detachments with either a tractional component or associated vitreous haemorrhage. The second patient also had a large, raised schisis cavity under vitreous traction, which obscured visualisation of the macula. Vitrectomy is indicated for some patients with congenital retinoschisis.

Child↗
PubMed1984

Effects of the CW YAG laser on the human iris and retina.

A CW YAG laser was used to coagulate retina and to produce an optical iridotomy in a human eye that was to be enucleated for malignant melanoma at the optic nerve head. Moderate coagulation with the CW YAG laser produced a deep choroidal reaction involving the outer portion of the retina. The inner structure of the fovea remained relatively unaffected. The nerve fiber over the coagulated vessels was unchanged. An optical iridotomy also was produced with the CW YAG. At least ten times more energy was needed to produce retinal photocoagulation with the CW YAG than is generally needed with the argon laser. Retrobulbar anesthesia should be used to prevent pain if extensive coagulation is done.

Cranial Nerve Neoplasms↗
PubMed1983

Comparison of imported with locally retrieved kidneys preserved by intracellular electrolyte flushing followed by cold storage.

Ice-cold intracellular electrolyte flushing followed by cold storage and economy air shipment is the cheapest method to share kidneys for transplantation. This study from 1 center compares 62 primary cadaver kidney grafts imported from other centers to 128 that were retrieved locally. Cold ischemia time was 36.4 plus or minus 8.6 hours (mean plus or minus standard deviation) in the imported group and 24.2 plus or minus 8.8 hours in the locally retrieved group. The significant increase in first week dialysis (71 versus 42 per cent) and 1-month serum creatinine nadirs (2.63 plus or minus 2.73 versus 1.78 plus or minus 1.04 mg./dl.) was explained by longer cold ischemia times in the imported kidney grafts. There were no significant differences between the 2 groups with respect to actuarial kidney graft survivals and serum creatinine levels at 1, 2 and 3 years. Intracellular electrolyte flushing followed by simple cold storage and air transportation provides kidney graft survivals and long-term kidney graft function at minimal expense when the kidneys are retrieved from beating-heart cadavers and have undergone minimal warm ischemia.

Cold Temperature↗
PubMed1983

Development of a scoring system for the Milani-Comparetti and Gidoni method of assessing neurologic abnormality in infancy.

This article reports the results of using a scoring system designed for the Milani-Comparetti and Gidoni method of neurologic examination of infants. The system was used in the assessment of 999 infants from the neonatal intensive care units affiliated with the Medical College of Wisconsin. The sample included all neonates who spent more than five days in the units from 1975 to 1978. Full assessments were conducted at 6 months and at 15 to 16 months corrected gestational age; additional assessments were scheduled by the physical therapists. For data analyses, the scores from the Milani-Comparetti and Gidoni method were summed; infants were subdivided into normal, transiently abnormal, and abnormal on the basis of the summed scores. Abnormal infants were further categorized on the basis of all information available. Several data analyses were performed to test the contribution of each item in separating normal, transiently abnormal, and abnormal infants and in distinguishing one type of abnormality from another. We conclude that the scoring system is useful in quantifying the degree of abnormality, in separating normality from abnormality, and in distinguishing among types of abnormality.

Aging↗
PubMed1983

Beneficial effect of pre-transplant splenectomy for leukopenia in primary cadaver kidney transplants.

Pre-transplant splenectomy is controversial. We compared 21 nondiabetic, transfused recipients of first cadaver kidney grafts who underwent pre-transplant splenectomy for steroid-resistant leukopenia to 114 without steroid-resistant leukopenia. Kidney graft survivals at 2 years were 80.2 plus or minus 8.9 and 48.5 plus or minus 5.3 per cent, respectively (p less than 0.05). The 2-year actuarial patient survivals were not significantly different (89.6 plus or minus 7.0 versus 87.8 plus or minus 3.9 per cent). Azathioprine doses and serum creatinine levels at 1 year were not significantly different. Pre-transplant splenectomy for steroid-resistant leukopenia resulted in a significant decrease in kidney graft losses owing to rejection without an increased risk of death of sepsis or thromboembolism.

Azathioprine↗
PubMed1982

Branching of olivary axons to innervate pairs of sagittal zones in the cerebellar anterior lobe of the cat.

Four of the eight sagittal zones in the cortex of the cerebellar anterior lobe, the x, c1, c3 and d2 zones, receive similar climbing fibre input from the ipsilateral forelimb through pathways ascending in the dorsal funiculus (DF-SOCPs) and have disynaptic relays in the main cuneate nucleus (Ekerot and Larson 1979a). The present investigation demonstrates that the forelimb areas of these four zones are innervated by climbing fibres from three groups of olivary neurones with branching axons (Fig. 6). The termination sites of climbing fibre branches were determined by identifying the low-threshold spots on the cerebellar surface from which short-latency (3.1-7.5 ms), "direct" climbing fibre responses could be evoked in Purkinje cells. In some Purkinje cells these responses were followed by late (8.2-13.5 ms) climbing fibre responses ("olivary reflex" responses). Each group projects to a pair of these zones which is separated by an intervening zone innervated from a private group of olivary neurones. The three groups of olivary neurones have been denoted the x-c1 group, the c1-c3 group, and the c3-d2 group in accordance with the zones they innervate. They project to the following areas: (a) The x-c1 group to the x zone in the vermal cortex and the lateral part of the c1 zone in the intermediate cortex; (b) the c1-c3 group to the medial parts of the c1 and c3 zones in the intermediate cortex; and (c) the c3-d2 group to the lateral part of the c3 zone in the intermediate cortex and the d2 zone in the extreme lateral part of the anterior lobe. Olivary axons belonging to the x-c1 and c1-c3 groups often send several climbing fibres to each projection area, whereas only single termination sites were found in the c3 zone for olivary axons belonging to the c3-d2 group. The two projection areas of each group of olivary neurons have a similar topographical organization: the areas innervated by the x-c1 group lack distinct somatotopical organization, whereas the areas innervated by the c1-c3 and c3-d2 groups have a detailed somatotopical representation of the ipsilateral forelimb. The low threshold spots for the late climbing fibre responses ("olivary reflex" responses) were restricted to the same sagittal strips as the low-threshold spots for the "direct" responses.

Afferent Pathways↗
PubMed1980

Termination in overlapping sagittal zones in cerebellar anterior lobe of mossy and climbing fiber paths activated from dorsal funiculus.

The termination patterns in the cerebellar anterior lobe of one mossy fiber path, the exteroceptive component of the cuneocerebellar tract (E-CCT), and one climbing fiber system, the dorsal spino-olivocerebellar paths (DF-SOCPs), which both relay in the main cuneate nucleus, were compared in the cat. The E-CCT terminates in the ipsilateral half of the anterior lobe in five sagittal zones which overlap five of the eight zones activated from the DF-SOCPs. In at least one zone the E-CCT projection has a somatotopical organization which is similar to and overlaps that of the DF-SOCP.

Afferent Pathways↗
PubMed1980

Modification of rabbit corneal curvature with use of carbon dioxide laser burns.

Carbon dioxide laser burns of varied intensity, location, and pattern were produced on rabbit corneas. Evaluation of the parameters required to produce an optimal corneal lesion showed that lesions made with 8 W caused perforation of rabbit corneas. Various laser burn patterns were studied for their effect on the rabbit corneal curvature. This was followed by comparison of effect of laser burns on corneal curvature with that of untreated contralateral eyes. The effects of the burns on the corneal curvative were measured for 12 weeks with use of a standard keratometer in the 90 degree and 180 degrees axes. No significant changes in the corneal curvature were noted in the experimental versus the control eyes. Carbon dioxide laser burns were not effective in modifying corneal curvature in this study.

Animals↗
PubMed1980

Anti-inflammatory action of topical indomethacin.

Topically applied indomethacin before and after pars plana lensectomy-vitrectomy in an experimental rabbit model reduces postoperative inflammation, as demonstrated by a statistically significant inhibition of protein elevation in the ocular fluid.

Administration, Topical↗